Evidence map›Paper›PMID 19734458›Full record

Trial reportJournal of dental research2009

Biomimetic remineralization of resin-bonded acid-etched dentin.

F R Tay, D H Pashley

Abstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of dental research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
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  5. Trial
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  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Evolution of Dental Resin Adhesives-A Comprehensive Review.Journal of functional biomaterials · 2025
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

F R TayDepartment of Endodontics, School of Dentistry, Medical College of Georgia, Augusta, GA 30912-1129, USA. FTAY@mcg.edu
D H Pashley

Funding

Biomimetic remineralization of resin-dentin bondsR21DE019213 · NIDCR · AUGUSTA UNIVERSITY · PI TAY, FRANKLIN CHI MENG · 2009 to 2010
$362k
NIDCR NIH HHS R21 DE019213NIDCR NIH HHS R21 DE019213-01
6 · The paper itself

Abstract

Degradation of denuded collagen within adhesive resin-infiltrated dentin is a pertinent problem in dentin bonding. A biomimetic remineralization scheme that incorporates non-classic crystallization pathways of fluidic amorphous nanoprecursors and mesoscopic transformation has been successful in remineralizing resin-free, acid-etched dentin, with evidence of intrafibrillar and interfibrillar remineralization. This study tested the hypothesis that biomimetic remineralization provides a means for remineralizing incompletely infiltrated resin-dentin interfaces created by etch-and-rinse adhesives. The remineralization medium consists of a Portland cement/simulated body fluid that includes polyacrylic acid and polyvinylphosphonic acid biomimetic analogs for amorphous calcium phosphate dimension regulation and collagen targeting. Both interfibrillar and intrafibrillar apatites became readily discernible within the hybrid layers after 2-4 months. In addition, intra-resin apatite clusters were deposited within the porosities of the adhesive resin matrices. The biomimetic remineralization scheme provides a proof-of-concept for the adoption of nanotechnology as an alternative strategy to extend the longevity of resin-dentin bonds.

Indexed as

Dental BondingAcid Etching, DentalAcrylic ResinsBiomimetic MaterialsBisphenol A-Glycidyl MethacrylateCalcium CompoundsCalcium PhosphatesCalcium SulfateCollagenComposite ResinsCrystallizationDental CementsDental MaterialsDentinDentin-Bonding AgentsHumansAcrylic ResinsBis-GMA, BPDM, HEMA dental-bonding resinBisphenol A-Glycidyl MethacrylateCalcium Compoundscalcium phosphateCalcium Phosphatescalcium silicateCalcium Sulfatecarbopol 940CollagenComposite ResinsDental CementsDental MaterialsDentin-Bonding AgentsMethacrylatesOrganophosphonatesphosphoric acidPhosphoric AcidsPolyvinylsResin CementsSaliva, ArtificialSilicatesSingle Bond Plus

Identifiers

PMID19734458
PMCPMC2874868

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.