ArticleThe Plant cell2009
Medicago N2-fixing symbiosomes acquire the endocytic identity marker Rab7 but delay the acquisition of vacuolar identity.
Article in The Plant cell, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
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Who cites it
65 citing papers in PubMed, 155 citations in OpenAlex.
- ESN3, a nodule-specific small peptide essential for symbiotic nitrogen fixation in Medicago truncatula.The New phytologist · 2026Article
- Symbiosis-associated UMAMIT transporters required for establishing efficient nitrogen fixation in Medicago truncatula.The New phytologist · 2026Article
- Cullin 3 substrate-adaptor protein 1 (MtCSP1) modulates nodulation through interaction with the GTPase ARFA1.Scientific reports · 2026Article
- Morphology ofPlants (Basel, Switzerland) · 2025Article
- Review
- A mobile DELLA controls Medicago truncatula root cortex patterning to host arbuscular mycorrhizal fungi.Nature plants · 2025Article
- Cellular basis of legume-rhizobium symbiosis.Plant communications · 2024Review
- Autophagy and Symbiosis: Membranes, ER, and Speculations.International journal of molecular sciences · 2024Review
- Comparison of the Formation of Plant-Microbial Interface inInternational journal of molecular sciences · 2023Article
- GmNAC039 and GmNAC018 activate the expression of cysteine protease genes to promote soybean nodule senescence.The Plant cell · 2023Article
- A signal peptide peptidase is required for ER-symbiosome proximal association and protein secretion.Nature communications · 2023Article
- Antibacterial Properties of Mesoporous Silica Nanoparticles Modified with Fluoroquinolones and Copper or Silver Species.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Rapid Changes to Endomembrane System of Infected Root Nodule Cells to Adapt to Unusual Lifestyle.International journal of molecular sciences · 2023Review
- The putative transporter MtUMAMIT14 participates in nodule formation in Medicago truncatula.Scientific reports · 2023Article
- RAB7 GTPases as coordinators of plant endomembrane traffic.Frontiers in plant science · 2023Review
- Hybrid Nanosystems Based on Nicotinate-Functionalized Mesoporous Silica and Silver Chloride Nanoparticles Loaded with Phenytoin for PreventingPharmaceuticals (Basel, Switzerland) · 2022Article
- MtEFD and MtEFD2: Two transcription factors with distinct neofunctionalization in symbiotic nodule development.Plant physiology · 2022Article
- Phylogenetic and Expression Studies of Small GTP-Binding Proteins inPlants (Basel, Switzerland) · 2022Article
- Article
- Potassium content diminishes in infected cells of Medicago truncatula nodules due to the mislocation of channels MtAKT1 and MtSKOR/GORK.Journal of experimental botany · 2021Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rhizobium bacteria form N(2)-fixing organelles, called symbiosomes, inside the cells of legume root nodules. The bacteria are generally thought to enter the cells via an endocytosis-like process. To examine this, we studied the identity of symbiosomes in relation to the endocytic pathway. We show that in Medicago truncatula, the small GTPases Rab5 and Rab7 are endosomal membrane identity markers, marking different (partly overlapping) endosome populations. Although symbiosome formation is considered to be an endocytosis-like process, symbiosomes do not acquire Rab5 at any stage during their development, nor do they accept the trans-Golgi network identity marker SYP4, presumed to mark early endosomes in plants. By contrast, the endosomal marker Rab7 does occur on symbiosomes from an early stage of development when they have stopped dividing up to the senescence stage. However, the symbiosomes do not acquire vacuolar SNAREs (SYP22 and VTI11) until the onset of their senescence. By contrast, symbiosomes acquire the plasma membrane SNARE SYP132 from the start of symbiosome formation throughout their development. Therefore, symbiosomes appear to be locked in a unique SYP132- and Rab7-positive endosome stage and the delay in acquiring (lytic) vacuolar identity (e.g., vacuolar SNAREs) most likely ensures their survival and maintenance as individual units.
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