ReviewMicrobes and infection2009
Viral inhibitors reveal overlapping themes in regulation of cell death and innate immunity.
Review in Microbes and infection, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Review
- The UL16 protein of HSV-1 promotes the metabolism of cell mitochondria by binding to ANT2 protein.Scientific reports · 2021Article
- How do viruses control mitochondria-mediated apoptosis?Virus research · 2015Review
- Immunity, suicide or both? Ecological determinants for the combined evolution of anti-pathogen defense systems.BMC evolutionary biology · 2015Article
- Article
- Tax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cells.The Journal of biological chemistry · 2012Article
- Human herpesvirus 8 interferon regulatory factor-mediated BH3-only protein inhibition via Bid BH3-B mimicry.PLoS pathogens · 2012Article
- The vaccinia virus-encoded Bcl-2 homologues do not act as direct Bax inhibitors.Journal of virology · 2012Article
- Deletion of the viral anti-apoptotic gene F1L in the HIV/AIDS vaccine candidate MVA-C enhances immune responses against HIV-1 antigens.PloS one · 2012Article
- Structural determinants of caspase-9 inhibition by the vaccinia virus protein, F1L.The Journal of biological chemistry · 2011Article
- Inhibition of RNA interference and modulation of transposable element expression by cell death in Drosophila.Genetics · 2011Article
- Induction of Noxa-mediated apoptosis by modified vaccinia virus Ankara depends on viral recognition by cytosolic helicases, leading to IRF-3/IFN-β-dependent induction of pro-apoptotic Noxa.PLoS pathogens · 2011Article
- Broad-spectrum antiviral therapeutics.PloS one · 2011Article
- Curating the innate immunity interactome.BMC systems biology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many viruses regulate a crucial point in the apoptotic pathway by expressing viral Bcl-2 homologues, which have become useful tools to investigate the mechanisms behind the control of the mitochondrial checkpoint of apoptosis. Concurrently, a number of viral inhibitors of innate immune signalling have been instrumental tools in the discovery of key host pathways. Here we discuss how viral inhibitors of the apoptotic and innate signalling pathways have further enhanced the understanding of both research fields and are beginning to shed light on how these two pathways converge.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.