ReviewClinics in perinatology2009
Fetal effects of psychoactive drugs.
Review in Clinics in perinatology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 93 citations in OpenAlex.
- Neurobehavioral Profiles in Low-Risk Infants: Associations With Prenatal Maternal Biobehavior and Birth Characteristics.Developmental psychobiology · 2025Article
- Maternal antidepressant effects on the fetal nonstress test.Archives of women's mental health · 2025Observational
- Prenatal substance exposure and infant neurodevelopment: a review of magnetic resonance imaging studies.Frontiers in human neuroscience · 2025Review
- Fetal behavior and gestational serotonin reuptake inhibitor exposure: relationships between behavior, drug dosage, plasma drug level, and a measure of drug bioeffect.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Prenatal Substance Exposure.Annual review of developmental psychology · 2023Article
- Opioid, methamphetamine, and polysubstance use: perinatal outcomes for the mother and infant.Frontiers in pediatrics · 2023Review
- Effect of prenatal exposure of green tea extract on the developing central nervous system of rat fetuses; histological, immune-histochemical and ultrastructural studies.Saudi journal of biological sciences · 2021Article
- The Adverse Effects of Prenatal METH Exposure on the Offspring: A Review.Frontiers in pharmacology · 2021Review
- Maternal Serotonin Reuptake Inhibitor Antidepressants Have Acute Effects on Fetal Heart Rate Variability in Late Gestation.Frontiers in psychiatry · 2021Article
- Reduced fractional anisotropy in projection, association, and commissural fiber networks in neonates with prenatal methamphetamine exposure.Developmental neurobiology · 2020Article
- Prenatal antidepressant exposures and gastrointestinal complaints in childhood: A gut-brain axis connection?Developmental psychobiology · 2020Article
- Article
- Caffeine Consumption During Pregnancy Accelerates the Development of Cognitive Deficits in Offspring in a Model of Tauopathy.Frontiers in cellular neuroscience · 2019Article
- Major depressive disorder during pregnancy: Psychiatric medications have minimal effects on the fetus and infant yet development is compromised.Development and psychopathology · 2018Article
- Impact of maternal prenatal smoking on fetal to infant neurobehavioral development.Development and psychopathology · 2018Article
- The Epigenetic Link between Prenatal Adverse Environments and Neurodevelopmental Disorders.Genes · 2017Review
- Neurotransmitter signaling pathways required for normal development in Xenopus laevis embryos: a pharmacological survey screen.Journal of anatomy · 2016Article
- Safety of Selective Serotonin Reuptake Inhibitors in Pregnancy: A Review of Current Evidence.CNS drugs · 2016Review
- Article
- Cross-national comparison of prenatal methamphetamine exposure on infant and early child physical growth: a natural experiment.Prevention science : the official journal of the Society for Prevention Research · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Psychoactive drug use by pregnant women has the potential to effect fetal development; the effects are often thought to be drug-specific and gestational age dependent. This article describes the effects of three drugs with similar molecular targets that involve monoaminergic transmitter systems: cocaine, methamphetamine, and selective serotonin re-uptake inhibitors (SSRIs) used to treat maternal depression during pregnancy. We propose a possible common epigenetic mechanism for their potential effects on the developing child. We suggest that exposure to these substances acts as a stressor that affects fetal programming, disrupts fetal placental monoamine transporter expression and alters neuroendocrine and neurotransmitter system development. We also discuss neurobehavioral techniques that may be useful in the early detection of the effects of in utero drug exposure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.