ReviewClinics in perinatology2009
Fetal hypoxia insults and patterns of brain injury: insights from animal models.
Review in Clinics in perinatology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
84 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prognostic Value of Clinical Tests in Neonates With Hypoxic-Ischemic Encephalopathy Treated With Therapeutic Hypothermia: A Systematic Review and Meta-Analysis.Frontiers in neurology · 2020Pooled it
- A Systematic Review of Magnesium Sulfate for Perinatal Neuroprotection: What Have We Learnt From the Past Decade?Frontiers in neurology · 2020Pooled it
- Noninvasive assessment of fetal metabolic acidemia by automated analysis of cardiac function using color tissue Doppler imaging in a sheep model.Scientific reports · 2026Article
- A reduction in large animal research threatens the perinatal translation research pipeline.Pediatric research · 2026Review
- The Role of 100% Oxygen in the Resuscitation and Neurologic Recovery of Neonates Born with Perinatal Depression and Arrested Circulation.The Journal of pediatrics · 2026Article
- Article
- A Specific Haplotype of theDiagnostics (Basel, Switzerland) · 2025Article
- Sex dimorphism in brain cell death after hypoxia-ischemia in newborn piglets.Pediatric research · 2025Article
- Analysis of Energy Metabolism and Lipid Spatial Distribution in Hypoxic-Ischemic Encephalopathy Revealed by MALDI-MSI.Biomedicines · 2025Article
- Inflammation mediated brain damage and cytokine expression in a maternally derived murine model for preterm hypoxic-ischemic encephalopathy.Frontiers in systems biology · 2025Article
- A Multiscale Mathematical Model for Fetal Gas Transport and Regulatory Systems During Second Half of Pregnancy.International journal for numerical methods in biomedical engineering · 2025Article
- In vitro effect of vitaminBToxicology research · 2024Article
- Rapid detection of fetal compromise using input length invariant deep learning on fetal heart rate signals.Scientific reports · 2024Article
- MRI predictors of long-term outcomes of neonatal hypoxic ischaemic encephalopathy: a primer for radiologists.The British journal of radiology · 2024Review
- Intrauterine inflammation and postnatal intravenous dopamine alter the neurovascular unit in preterm newborn lambs.Journal of neuroinflammation · 2024Article
- Establishment and Validation of a Model for Fetal Neural Ischemia Using Necrotic Core-Free Human Spinal Cord Organoids.Stem cells translational medicine · 2024Article
- Edaravone Confers Neuroprotective, Anti-inflammatory, and Antioxidant Effects on the Fetal Brain of a Placental-ischemia Mouse Model.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2023Article
- Subcortical brain volumes in neonatal hypoxic-ischemic encephalopathy.Pediatric research · 2023Article
- Velocity Time Integral: A Novel Method for Assessing Fetal Anemia.Children (Basel, Switzerland) · 2023Article
- Creatine in the fetal brain: A regional investigation of acute global hypoxia and creatine supplementation in a translational fetal sheep model.Frontiers in cellular neuroscience · 2023Article
24 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The outcome of perinatal hypoxiaischemia is highly variable, with only a very broad relationship to the 'severity' of oxygen debt as shown by peripheral base deficit and the risk of damage. The present article examines the pathophysiology of asphyxial injury. We dissect the multiple factors that modify the risk of injury, including the depth ('severity'), duration, and repetition of the insult, the maturity, and condition of the fetus, pre-existing hypoxia, and exposure to pyrexia and infection/inflammation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.