ArticleThe Journal of pediatrics2009
Childhood predictors of the metabolic syndrome in middle-aged adults: the Muscatine study.
Article in The Journal of pediatrics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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Who cites it
22 citing papers in PubMed, 64 citations in OpenAlex.
- Risk factors and clinical presentation of coronary artery disease in young patients: a decade-long single-center experience.BMC cardiovascular disorders · 2026Article
- Cardiopulmonary Benefits of Exercise in Adolescents.Advances in experimental medicine and biology · 2026Review
- BMI trajectory and inflammatory effects on metabolic syndrome in adolescents.Pediatric research · 2023Article
- Building a model for predicting metabolic syndrome using artificial intelligence based on an investigation of whole-genome sequencing.Journal of translational medicine · 2022Article
- Progression of metabolic syndrome and associated cardiometabolic risk factors from prepuberty to puberty in children: The PUBMEP study.Frontiers in endocrinology · 2022Article
- Preventing Premature Atherosclerotic Disease.Current hypertension reports · 2020Review
- Promoting Cardiovascular Health in Early Childhood and Transitions in Childhood through Adolescence: A Workshop Report.The Journal of pediatrics · 2019Article
- Pediatric Hypertension: Are Pediatricians Following Guidelines?Journal of clinical hypertension (Greenwich, Conn.) · 2016Article
- Article
- Increased Risk of Obesity and Metabolic Dysregulation Following 12 Months of Second-Generation Antipsychotic Treatment in Children: A Prospective Cohort Study.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2015Article
- The Relationship Between Physical Activity and the Metabolic Syndrome Score in Children.Pediatric exercise science · 2015Article
- Introducing the Tehran Heart Center's Premature Coronary Atherosclerosis Cohort: THC-PAC Study.The journal of Tehran Heart Center · 2015Article
- Correlates of adiposity in a Caribbean pre-school population.Public health nutrition · 2014Article
- Socio-demographic and lifestyle factors for child's physical growth and adiposity rebound of Japanese children: a longitudinal study of the 21st century longitudinal survey in newborns.BMC public health · 2014Article
- Metabolic syndrome in youth: chimera or useful concept?Current diabetes reports · 2013Review
- Differences in the prevalence of metabolic syndrome in boys and girls based on various definitions.ARYA atherosclerosis · 2013Article
- Article
- The centre for healthy weights--shapedown BC: a family-centered, multidisciplinary program that reduces weight gain in obese children over the short-term.International journal of environmental research and public health · 2011Article
- Childhood obesity and cardiovascular disease: links and prevention strategies.Nature reviews. Cardiology · 2011Review
- Predicting cardiovascular risk in young adulthood from the metabolic syndrome, its component risk factors, and a cluster score in childhood.International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity · 2011Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo investigate the association between components of the metabolic syndrome (MetS) measured during childhood/adolescence, and adult MetS. STUDY
designThis investigation focused on members of the Muscatine Study Longitudinal Adult Cohort. Predictor variables were risk factor measurements obtained between 1970 and 1981 when cohort members participated in school survey examinations. Risk factor measurements obtained between 1982 and 2008 when cohort members participated in follow-up examinations as young and middle-aged adults were used for MetS classification.
results33.0% (29.7% of 474 women; 37.0% of 384 men) of cohort members were classified as having the MetS. The initial MetS classification occurred at ages ranging from 23 to 52 years, with a mean age of 37.2 years (SD = 7.4). Cohort members with the MetS had significantly higher body mass index, systolic blood pressure, and triglycerides at the time they participated in the school survey examinations (P < .0001). Estimated probabilities of remaining MetS free at age 35 for those whose school survey body mass index and triglyceride measurements were both <50th vs >/=75th percentiles were strikingly different (0.94 vs 0.42).
conclusionsBMI is the strongest childhood predictor of adult MetS. Early identification of at-risk children may reduce the burden of atherosclerotic cardiovascular disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.