ReviewBMC infectious diseases2009
Leptospirosis in the Asia Pacific region.
Review in BMC infectious diseases, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 146 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
146 citing papers in PubMed, 5 syntheses or guidelines pooled it, 374 citations in OpenAlex.
- Leptospirosis Seroprevalence in Humans and Livestock of East Africa: A Systematic Review and Meta-Analysis (2000-2024).Veterinary medicine and science · 2025Pooled it
- Rapid diagnostic test (Leptocheck-WB) for detection of acute leptospirosis: a meta-analysis of diagnostic accuracy.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022Pooled it
- Agricultural land-uses consistently exacerbate infectious disease risks in Southeast Asia.Nature communications · 2019Pooled it
- Diversity of infectious aetiologies of acute undifferentiated febrile illnesses in south and Southeast Asia: a systematic review.BMC infectious diseases · 2019Pooled it
- A systematic review of human and animal leptospirosis in the Pacific Islands reveals pathogen and reservoir diversity.PLoS neglected tropical diseases · 2018Pooled it
- Estimating the Burden of Leptospirosis among Febrile Subjects Aged below 20 Years in Kampong Cham Communities, Cambodia, 2007-2009.PloS one · 2016Trial
- Antibodies to Leptospira among blood donors in higher-risk areas of Australia: possible implications for transfusion safety.Blood transfusion = Trasfusione del sangue · 2015Trial
- Serum profiling of leptospirosis patients to investigate proteomic alterations.Journal of proteomics · 2012Trial
- Ecological Niche Modeling of PathogenicPathogens (Basel, Switzerland) · 2026Article
- Molecular epidemiology of rodent-borneJournal of medical microbiology · 2026Article
- Pathogenic Leptospira species identified in dogs and cats during neutering in Thailand.PLoS neglected tropical diseases · 2026Article
- Leptospirosis in Southeast Asia: Investigating Seroprevalence, Transmission Patterns, and Diagnostic Challenges.Tropical medicine and infectious disease · 2026Review
- Spatiotemporal dynamics and environmental trends of reported human leptospirosis in Sri Lanka, 2007-2024.Frontiers in public health · 2026Article
- Human leptospirosis in the central division of Fiji: a retrospective epidemiological study.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2025Article
- Understanding human-bat interactions and risk perceptions in rural Thailand: a qualitative study from Nakhon Sawan Province.Scientific reports · 2025Article
- Epidemiological, temporal, and geographic trends of leptospirosis in the United States, 2014-2020.PLoS neglected tropical diseases · 2025Article
- Case-control study of leptospirosis in Aotearoa New Zealand reveals behavioural, occupational, and environmental risk factors.Epidemiology and infection · 2025Article
- Spatio-temporal risk prediction of leptospirosis: A machine-learning-based approach.PLoS neglected tropical diseases · 2025Article
- Article
- Isolation and characterization of Leptospira licerasiae in Austrian swine - a first-time case report in Europe.BMC veterinary research · 2024Article
86 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLeptospirosis is a worldwide zoonotic infection that has been recognized for decades, but the problem of the disease has not been fully addressed, particularly in resource-poor, developing countries, where the major burden of the disease occurs. This paper presents an overview of the current situation of leptospirosis in the region. It describes the current trends in the epidemiology of leptospirosis, the existing surveillance systems, and presents the existing prevention and control programs in the Asia Pacific region.
methodsData on leptospirosis in each member country were sought from official national organizations, international public health organizations, online articles and the scientific literature. Papers were reviewed and relevant data were extracted.
resultsLeptospirosis is highly prevalent in the Asia Pacific region. Infections in developed countries arise mainly from occupational exposure, travel to endemic areas, recreational activities, or importation of domestic and wild animals, whereas outbreaks in developing countries are most frequently related to normal daily activities, over-crowding, poor sanitation and climatic conditions.
conclusionIn the Asia Pacific region, predominantly in developing countries, leptospirosis is largely a water-borne disease. Unless interventions to minimize exposure are aggressively implemented, the current global climate change will further aggravate the extent of the disease problem. Although trends indicate successful control of leptospirosis in some areas, there is no clear evidence that the disease has decreased in the last decade. The efficiency of surveillance systems and data collection varies significantly among the countries and areas within the region, leading to incomplete information in some instances. Thus, an accurate reflection of the true burden of the disease remains unknown.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.