Evidence map›Paper›PMID 19730919›Full record

ArticleGenes & nutrition2010

Longevity nutrients resveratrol, wines and grapes.

Istvan Lekli, Diptarka Ray, Dipak K Das

Abstract read
In one paragraph

Article in Genes & nutrition, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. A Comprehensive Study on the Antimicrobial Properties of Resveratrol as an Alternative Therapy.Evidence-based complementary and alternative medicine : eCAM · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Istvan LekliCardiovascular Research Center, University of Connecticut School of Medicine, Farmington, CT 06030-1110 USA.
Diptarka Ray
Dipak K Das

Funding

PHOSPHOLIPIDS IN MYOCARDIAL REPERFUSION INJURYR01HL034360 · NHLBI · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI DAS, DIPAK K · 1987 to 2009
$2.8M
MYOCARDIAL PRESERVATION DURING ISCHEMIC ARRESTR01HL022559 · NHLBI · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI DAS, DIPAK K · 1985 to 2008
$2.7M
NHLBI NIH HHS R01 HL022559NHLBI NIH HHS R01 HL034360
6 · The paper itself

Abstract

A mild-to-moderate wine drinking has been linked with reduced cardiovascular, cerebrovascular, and peripheral vascular risk as well as reduced risk due to cancer. The reduced risk of cardiovascular disease associated with wine drinking is popularly known as French Paradox. A large number of reports exist in the literature indicating that resveratrol present in wine is primarily responsible for the cardioprotection associated with wine. Recently, resveratrol was shown to extend life span in yeast through the activation of longevity gene SirT1, which is also responsible for the longevity mediated by calorie restriction. This review summarizes the reports available on the functional and molecular biological aspects of resveratrol, wine and grapes in potentiating the longevity genes.

Indexed as

LongevityRed wineResveratrolSirT1

Identifiers

PMID19730919
PMCPMC2820197

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.