ArticlePLoS genetics2009
Phytochrome B and histone deacetylase 6 control light-induced chromatin compaction in Arabidopsis thaliana.
Article in PLoS genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
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Who cites it
57 citing papers in PubMed, 141 citations in OpenAlex.
- Phytochrome-mediated light perception in dodders drives haustorium development through epigenetic mechanisms.Plant & cell physiology · 2026Article
- Uncovering adaptation with a new Arabidopsis thaliana multiparent intercross population.Genetics · 2026Article
- Single-molecule views of chromatin accessibility and structure during photomorphogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- BrHDA6 mediates nonhistone deacetylation of BrSOT12 to positively regulate downy mildew resistance inHorticulture research · 2025Article
- Chromatin sensing: integration of environmental signals to reprogram plant development through chromatin regulators.Journal of experimental botany · 2024Review
- What is going on inside of phytochrome B photobodies?The Plant cell · 2024Review
- Distinguishing individual photobodies using Oligopaints reveals thermo-sensitive and -insensitive phytochrome B condensation at distinct subnuclear locations.Nature communications · 2024Article
- Role of Epigenetic Factors in Response to Stress and Establishment of Somatic Memory of Stress Exposure in Plants.Plants (Basel, Switzerland) · 2023Review
- UV-B-induced modulation of constitutive heterochromatin content in Arabidopsis thaliana.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023Article
- Genome-Wide Identification of Histone Deacetylases and Their Roles Related with Light Response in Tartary Buckwheat (International journal of molecular sciences · 2023Article
- Shade-Induced Leaf Senescence in Plants.Plants (Basel, Switzerland) · 2023Review
- Moonlight Is Perceived as a Signal Promoting Genome Reorganization, Changes in Protein and Metabolite Profiles and Plant Growth.Plants (Basel, Switzerland) · 2023Article
- Epigenetic control of plant senescence and cell death and its application in crop improvement.Frontiers in plant science · 2023Review
- Parental methylation mediates how progeny respond to environments of parents and of progeny themselves.Annals of botany · 2022Article
- Light, chromatin, action: nuclear events regulating light signaling in Arabidopsis.The New phytologist · 2022Review
- 2D morphometric analysis of Arabidopsis thaliana nuclei reveals characteristic profiles of different cell types and accessions.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2022Article
- TheFrontiers in genetics · 2022Article
- Phytochrome-Mediated Light Perception Affects Fruit Development and Ripening Through Epigenetic Mechanisms.Frontiers in plant science · 2022Article
- H3.1 Eviction Marks Female Germline Precursors in Arabidopsis.Plants (Basel, Switzerland) · 2020Article
- Light and Abscisic Acid Coordinately Regulate Greening of Seedlings.Plant physiology · 2020Article
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Authors and funding
14 authors at 4 institutions in 3 countries.
Funding
Abstract
Natural genetic variation in Arabidopsis thaliana exists for many traits and often reflects acclimation to local environments. Studying natural variation has proven valuable in the characterization of phenotypic traits and, in particular, in identifying genetic factors controlling these traits. It has been previously shown that chromatin compaction changes during development and biotic stress. To gain more insight into the genetic control of chromatin compaction, we investigated the nuclear phenotype of 21 selected Arabidopsis accessions from different geographic origins and habitats. We show natural variation in chromatin compaction and demonstrate a positive correlation with latitude of geographic origin. The level of compaction appeared to be dependent on light intensity. A novel approach, combining Quantitative Trait Locus (QTL) mapping and microscopic examination, pointed at PHYTOCHROME-B (PHYB) and HISTONE DEACETYLASE-6 (HDA6) as positive regulators of light-controlled chromatin compaction. Indeed, mutant analyses demonstrate that both factors affect global chromatin organization. HDA6, in addition, strongly promotes the light-mediated compaction of the Nucleolar Organizing Regions (NORs). The accession Cape Verde Islands-0 (Cvi-0), which shows sequence polymorphism in the PHYB gene and in the HDA6 promotor, resembles the hda6 mutant in having reduced chromatin compaction and decreased methylation levels of DNA and histone H3K9 at the NORs. We provide evidence that chromatin organization is controlled by light intensity. We propose that chromatin plasticity is associated with acclimation of Arabidopsis to its environment. The polymorphic alleles such as PHYB and HDA6 control this process.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.