ReviewCirculation journal : official journal of the Japanese Circulation Society2009
Sex/gender medicine. The biological basis for personalized care in cardiovascular medicine.
Review in Circulation journal : official journal of the Japanese Circulation Society, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sex consideration in diet-biomarker-related indices: a systematic review.Public health nutrition · 2018Pooled it
- Mitochondria, Sex, and Cardiovascular Disease: A Complex Interplay.International journal of molecular sciences · 2025Review
- The impact of sex on blood pressure.Current opinion in nephrology and hypertension · 2025Review
- Sex-Associated Differences in Clinical Outcomes After Septal Reduction Therapies in Hypertrophic Cardiomyopathy.Mayo Clinic proceedings · 2024Article
- Gender differences in congenital heart defects: a narrative review.Translational pediatrics · 2023Review
- Microvascular Aging and Eicosanoids-Women's Evaluation of Systemic Aging Tenacity ("You are never too old to become younger!") Specialized Center of Research Excellence on Sex Differences Career Enhancement Core: Building the Future.Journal of women's health (2002) · 2023Article
- Sex Differences in Moderate to Severe Psoriasis: Analysis of the Psoriasis Longitudinal Assessment and Registry.Journal of psoriasis and psoriatic arthritis · 2022Article
- Sex Differences in Cardiovascular Diseases: A Matter of Estrogens, Ceramides, and Sphingosine 1-Phosphate.International journal of molecular sciences · 2022Review
- Sexual dimorphism in cardiometabolic and cardiac mitochondrial function in obese rats following sex hormone deprivation.Nutrition & diabetes · 2022Article
- Research on Women's Health: Ready for the Future.Journal of women's health (2002) · 2022Article
- Global Research Trends of Gender-Related Artificial Intelligence in Medicine Between 2001-2020: A Bibliometric Study.Frontiers in medicine · 2022Article
- Sex differences in health and disease: A review of biological sex differences relevant to cancer with a spotlight on glioma.Cancer letters · 2021Review
- Sex-Steroid Signaling in Lung Diseases and Inflammation.Advances in experimental medicine and biology · 2021Article
- Impact of gender on heart failure presentation in non-obstructive hypertrophic cardiomyopathy.Heart and vessels · 2020Article
- Y Chromosome, Hypertension and Cardiovascular Disease: Is Inflammation the Answer?International journal of molecular sciences · 2019Review
- Sex differences in the central and peripheral manifestations of ischemia-induced heart failure in rats.American journal of physiology. Heart and circulatory physiology · 2019Article
- Women with hypertrophic cardiomyopathy have worse survival.European heart journal · 2017Article
- Exercise vasodilation is greater in women: contributions of nitric oxide synthase and cyclooxygenase.European journal of applied physiology · 2015Article
- Sex steroid signaling: implications for lung diseases.Pharmacology & therapeutics · 2015Review
- Perceived Relevance of Gender-Specific Differences in Gastrointestinal Medicine and Surgery: Results of a Survey.Viszeralmedizin · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Sex differences in morbidity and mortality associated with cardiovascular disease have been recognized by the medical community for decades. Investigation into the underlying biological basis of these differences was largely neglected by the scientific community until a report released by the Institute of Medicine in the United States in 2001 "Exploring the Biological Contributions to Human Health: Does Sex Matter?" Recommendations from this report included the need for more accurate use of the terms "sex" and "gender", better tools and resources to study the biological basis of sex differences, integration of findings from different levels of biological organization and continued synergy between basic and clinical researchers. Ten years after the Institute's report, this review evaluates some of the sex differences in cardiovascular disease, reviews new approaches to study sex differences and emphasizes areas where further research is required. In the era of personalized medicine, the study of the biological basis of sex differences promises to optimize preventive, diagnostic and therapeutic strategies for cardiovascular disease in men and women, but will require diligence by the scientific and medical communities to remember that sex does matter.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.