ReviewThe Journal of clinical investigation2009
A decade of molecular pathogenomic analysis of group A Streptococcus.
Review in The Journal of clinical investigation, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01558804 (Gene Expression in Isolates of Group A Streptococci Recovered From Patients Who Are Carriers), which is not on this map. Cited by 47 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Gene Expression in Isolates of Group A Streptococci Recovered From Patients Who Are Carriers
Who cites it
47 citing papers in PubMed, 87 citations in OpenAlex.
- Trial
- Locked Nucleic Acid and Minor Groove Binder Probes Improve the Specificity of Isothermal Amplification Detection.Analytical chemistry · 2026Article
- Post-COVID-19-pandemic changes and clinical characteristics of invasive group a streptococcal infections from 2015 to 2023.Infection · 2025Article
- Signaling Peptide SpoV Is Essential forMicroorganisms · 2021Article
- Streptolysin O concentration and activity is central to in vivo phenotype and disease outcome in Group A Streptococcus infection.Scientific reports · 2021Article
- Combinatorial liposomal peptide vaccine induces IgA and confers protection against influenza virus and bacterial super-infection.Clinical & translational immunology · 2021Article
- Elevated risk of invasive group A streptococcal disease and host genetic variation in the human leucocyte antigen locus.Genes and immunity · 2020Article
- Recent Advances in the Development of Peptide Vaccines and Their Delivery Systems Against Group A Streptococcus.Vaccines · 2019Review
- Hydrogen Peroxide Production of Group A Streptococci (GAS) is emm-Type Dependent and Increased at Low Temperatures.Current microbiology · 2019Article
- Sortases, Surface Proteins, and Their Roles inMicrobiology spectrum · 2019Article
- Antimicrobial resistance in beta-haemolytic streptococci in India: A four-year study.The Indian journal of medical research · 2018Article
- Endothelial cells are intrinsically defective in xenophagy of Streptococcus pyogenes.PLoS pathogens · 2017Article
- The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection.The Journal of clinical investigation · 2017Article
- Rapid Emergence of a New Clone Impacts the Population at Risk and Increases the Incidence of TypeOpen forum infectious diseases · 2017Article
- Genomic Landscape of Intrahost Variation in Group A Streptococcus: Repeated and Abundant Mutational Inactivation of the fabT Gene Encoding a Regulator of Fatty Acid Synthesis.Infection and immunity · 2016Article
- Genome Analysis of Streptococcus pyogenes Associated with Pharyngitis and Skin Infections.PloS one · 2016Article
- The Association between Invasive Group A Streptococcal Diseases and Viral Respiratory Tract Infections.Frontiers in microbiology · 2016Review
- Phosphorylation events in the multiple gene regulator of group A Streptococcus significantly influence global gene expression and virulence.Infection and immunity · 2015Article
- A naturally occurring single amino acid replacement in multiple gene regulator of group A Streptococcus significantly increases virulence.The American journal of pathology · 2015Article
- Deriving group A Streptococcus typing information from short-read whole-genome sequencing data.Journal of clinical microbiology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Molecular pathogenomic analysis of the human bacterial pathogen group A Streptococcus has been conducted for a decade. Much has been learned as a consequence of the confluence of low-cost DNA sequencing, microarray technology, high-throughput proteomics, and enhanced bioinformatics. These technical advances, coupled with the availability of unique bacterial strain collections, have facilitated a systems biology investigative strategy designed to enhance and accelerate our understanding of disease processes. Here, we provide examples of the progress made by exploiting an integrated genome-wide research platform to gain new insight into molecular pathogenesis. The studies have provided many new avenues for basic and translational research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.