ReviewMolecular aspects of medicine2009
The genome and variation of Bacillus anthracis.
Review in Molecular aspects of medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 98 citations in OpenAlex.
- Core Proteome Subtractive Genomics Reveals Potential Therapeutic Targets in Bacillus anthracis.Current microbiology · 2026Article
- Genomic outbreak investigation of biosafety-level-3 pathogens using nanopore sequencing.Microbial genomics · 2026Article
- Decoding Virulence Mechanisms ofMicroorganisms · 2026Article
- Genomic adaptability and virulence of Bacillus anthracis: a machine learning-based pan-genome and comparative analysis.BMC genomics · 2026Article
- Development of Nanopore amplicon sequencing method for culture-free genotyping ofFrontiers in microbiology · 2026Article
- Quarantine as filter: a conceptual framework from early modern Venice.Evolution, medicine, and public health · 2026Review
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- Bacillus cereus biovar anthracis causes inhalational anthrax-like disease in rabbits that is treatable with medical countermeasures.PLoS neglected tropical diseases · 2025Article
- Persistence in time: the hunt forApplied and environmental microbiology · 2025Article
- Antimicrobial Resistance Profile, Whole-Genome Sequencing and Core Genome Multilocus Sequence Typing ofAntibiotics (Basel, Switzerland) · 2024Article
- Identification of the molecular characteristics ofVeterinary world · 2022Article
- Molecular Typing of UkrainianMicroorganisms · 2022Article
- Genetic Diversity of AustralianMicroorganisms · 2020Article
- Review: The risk of contracting anthrax from spore-contaminated soil - A military medical perspective.European journal of microbiology & immunology · 2020Article
- Genetic diversity of Bacillus anthracis Ames lineage strains in China.BMC infectious diseases · 2020Article
- Using old antibiotics to treat ancient bacterium-β-lactams for Bacillus anthracis meningitis.PloS one · 2020Article
- You Can'tFrontiers in microbiology · 2020Review
- Phages for Phage Therapy: Isolation, Characterization, and Host Range Breadth.Pharmaceuticals (Basel, Switzerland) · 2019Review
- Lineage-specific plasmid acquisition and the evolution of specialized pathogens in Bacillus thuringiensis and the Bacillus cereus group.Molecular ecology · 2018Article
- Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
The Bacillus anthracis genome reflects its close genetic ties to Bacillus cereus and Bacillus thuringiensis but has been shaped by its own unique biology and evolutionary forces. The genome is comprised of a chromosome and two large virulence plasmids, pXO1 and pXO2. The chromosome is mostly co-linear among B. anthracis strains and even with the closest near neighbor strains. An exception to this pattern has been observed in a large inversion in an attenuated strain suggesting that chromosome co-linearity is important to the natural biology of this pathogen. In general, there are few polymorphic nucleotides among B. anthracis strains reflecting the short evolutionary time since its derivation from a B. cereus-like ancestor. The exceptions to this lack of diversity are the variable number tandem repeat (VNTR) loci that exist in genic and non genic regions of the chromosome and both plasmids. Their variation is associated with high mutability that is driven by rapid insertion and deletion of the repeats within an array. A notable example is found in the vrrC locus which is homologous to known DNA translocase genes from other bacteria.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.