ReviewClinical medicine (London, England)2009
Human umbilical cord blood stem cells, myocardial infarction and stroke.
Review in Clinical medicine (London, England), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 45 citations in OpenAlex.
- The Role of Narrative Medicine and Lean Management in Umbilical Cord Blood Donation: A Story of Success.Healthcare (Basel, Switzerland) · 2025Article
- Potential Mechanism and Perspectives of Mesenchymal Stem Cell Therapy for Ischemic Stroke: A Review.Global medical genetics · 2024Review
- Knowledge, Attitudes, and Practices of Pregnant Women and Hospital Staff Regarding Umbilical Cord Blood Banking: Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2024Review
- Stem Cell Differentiation into Cardiomyocytes: Current Methods and Emerging Approaches.Stem cell reviews and reports · 2022Review
- Review
- Upcycling umbilical cords: bridging regenerative medicine with neonatology.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2019Review
- HUCMNCs protect vascular endothelium and prevent ISR after endovascular interventional therapy for vascular diseases in T2DM rabbits.Molecular and cellular biochemistry · 2017Article
- Cell therapies for pancreatic beta-cell replenishment.Italian journal of pediatrics · 2016Review
- Translating G-CSF as an Adjunct Therapy to Stem Cell Transplantation for Stroke.Translational stroke research · 2015Article
- Stem cells and G-CSF for treating neuroinflammation in traumatic brain injury: aging as a comorbidity factor.Journal of neurosurgical sciences · 2014Review
- Magnetic resonance imaging of transplanted stem cell fate in stroke.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2014Review
- Stem Cell Banking for Regenerative and Personalized Medicine.Biomedicines · 2014Review
- Human Umbilical Cord Blood for Transplantation Therapy in Myocardial Infarction.Journal of stem cell research & therapy · 2013Article
- The effects of Hedgehog on the RNA-binding protein Msi1 in the proliferation and apoptosis of mesenchymal stem cells.PloS one · 2013Article
- Review
- The promise and perils of stem cell therapeutics.Cell stem cell · 2012Review
- Characterization of a novel umbilical cord lining cell with CD227 positivity and unique pattern of P63 expression and function.Stem cell reviews and reports · 2011Article
- Umbilical cord blood banking: an update.Journal of assisted reproduction and genetics · 2011Review
- Clinical trials for stem cell therapies.BMC medicine · 2011Review
- Challenges in umbilical cord blood stem cell banking for stem cell reviews and reports.Stem cell reviews and reports · 2010Review
Corrections and comments
- Commented on by
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Myocardial infarction (MI) and stroke are the first and third leading causes of death in the U.S.A. accounting for more than 1 in 3 deaths per annum. Despite interventional and pharmaceutical advances, the number of people diagnosed with heart disease is on the rise. Therefore, new clinical strategies are needed. Cell-based therapy holds great promise for treatment of these diseases and is currently under extensive preclinical as well as clinical trials. The source and types of stem cells for these clinical applications are questions of great interest. Human umbilical cord blood (hUCB) appears to be a logical candidate as a source of cells. hUCB is readily available, and presents little ethical challenges. Stem cells derived from hUCB are multipotent and immunologically naive. Here is a critical literature review of the beneficial effects of hUCB cell therapy in preclinical trials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.