ArticleJournal of neurology2010
Neurologic complications in adult living donor liver transplant patients: an underestimated factor?
Article in Journal of neurology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neurocognitive-neurological complications of liver transplantation: a review.Metabolic brain disease · 2010Pooled it
- Article
- Prevalence of cerebrovascular diseases that can cause hemorrhagic stroke in liver transplantation recipients: a 6-year comparative study with 24,681 healthy adults.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Article
- Factors Associated With Neurobehavioral Complications in Pediatric Abdominal Organ Transplant Recipients Identified Using Computable Composite Definitions.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2020Article
- Acute symptomatic seizure due to tacrolimus-related encephalopathy after liver transplantation: two case reports.The Journal of international medical research · 2019Article
- Imaging spectrum of central nervous system complications of hematopoietic stem cell and solid organ transplantation.Neuroradiology · 2017Review
- Comprehensive risk assessment for early neurologic complications after liver transplantation.World journal of gastroenterology · 2016Article
- Complications and mortality after adult to adult living donor liver transplantation: A retrospective cohort study.Annals of medicine and surgery (2012) · 2015Article
- Reprint of: Nutrition in the Management of Cirrhosis and its Neurological Complications.Journal of clinical and experimental hepatology · 2015Review
- Nutrition in the management of cirrhosis and its neurological complications.Journal of clinical and experimental hepatology · 2014Review
- Predictive factors of neurological complications and one-month mortality after liver transplantation.Frontiers in neurology · 2014Article
- Neurological complications post-liver transplantation: impact of nutritional status.Metabolic brain disease · 2013Review
- Impact of pretransplant hepatic encephalopathy on liver posttransplantation outcomes.International journal of hepatology · 2013Review
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Liver transplantation is the only curative treatment in patients with end-stage liver disease. Neurological complications (NC) are increasingly reported to occur in patients after cadaveric liver transplantation. This retrospective cohort study aims to evaluate the incidence and causes of NC in living donor liver transplant (LDLT) patients in our transplant center. Between August 1998 and December 2005, 121 adult LDLT patients were recruited into our study. 17% of patients experienced NC, and it occurred significantly more frequently in patients with alcoholic cirrhosis (42%) and autoimmune hepatitis (43%) as compared with patients with hepatitis B or C (9/10%, P = 0.013). The most common NC was encephalopathy (47.6%) followed by seizures (9.5%). The choice of immunosuppression by calcineurin inhibitor (Tacrolimus or Cyclosporin A) showed no significant difference in the incidence of NC (19 vs. 17%). The occurrence of NC did not influence the clinical outcome, since mortality rate, median ICU stay and length of hospital stay were similar between the two groups. Most patients who survived showed a nearly complete recovery of their NC. NCs occur in approximately 1 in 6 patients after LDLT and seem to be predominantly transient in nature, without major impact on clinical outcome.
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