ArticlePloS one2009
The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation.
Article in PloS one, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed.
- Toti: An integrated multi-omics database to decipher the epigenetic regulation of gene expression in totipotent stem cells.Stem cell reports · 2025Article
- Applications of Machine Learning (ML) and Mathematical Modeling (MM) in Healthcare with Special Focus on Cancer Prognosis and Anticancer Therapy: Current Status and Challenges.Pharmaceutics · 2024Review
- Flexible copula model for integrating correlated multi-omics data from single-cell experiments.Biometrics · 2023Article
- PSCRIdb: A database of regulatory interactions and networks of pluripotent stem cell lines.Journal of biosciences · 2020Article
- Myocardial differentiation is dependent upon endocardial signaling during early cardiogenesisDevelopment (Cambridge, England) · 2019Article
- The RNA exosome contributes to gene expression regulation during stem cell differentiation.Nucleic acids research · 2018Article
- Modulation of Differentiation Processes in Murine Embryonic Stem Cells Exposed to Parabolic Flight-Induced Acute Hypergravity and Microgravity.Stem cells and development · 2018Article
- Differentiation of Atrial Cardiomyocytes from Pluripotent Stem Cells Using the BMP Antagonist Grem2.Journal of visualized experiments : JoVE · 2016Article
- Murine Embryonic Stem Cell Plasticity Is Regulated through Klf5 and Maintained by Metalloproteinase MMP1 and Hypoxia.PloS one · 2016Article
- Neuronal developmental gene and miRNA signatures induced by histone deacetylase inhibitors in human embryonic stem cells.Cell death & disease · 2015Article
- Functional screen reveals essential roles of miR-27a/24 in differentiation of embryonic stem cells.The EMBO journal · 2015Article
- Databases and collaboration require standards for human stem cell research.Drug discovery today · 2015Review
- Web resources for stem cell research.Genomics, proteomics & bioinformatics · 2015Review
- Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the JNK signaling pathway.Stem cells (Dayton, Ohio) · 2014Article
- Ethanol alters the balance of Sox2, Oct4, and Nanog expression in distinct subpopulations during differentiation of embryonic stem cells.Stem cells and development · 2013Article
- ESCAPE: database for integrating high-content published data collected from human and mouse embryonic stem cells.Database : the journal of biological databases and curation · 2013Article
- Article
- Ethanol diverts early neuronal differentiation trajectory of embryonic stem cells by disrupting the balance of lineage specifiers.PloS one · 2013Article
- LIF-dependent signaling: new pieces in the Lego.Stem cell reviews and reports · 2012Review
- Article
Corrections and comments
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Authors and funding
36 authors.
Funding
Abstract
Embryonic stem (ES) cells have high self-renewal capacity and the potential to differentiate into a large variety of cell types. To investigate gene networks operating in pluripotent ES cells and their derivatives, the "Functional Genomics in Embryonic Stem Cells" consortium (FunGenES) has analyzed the transcriptome of mouse ES cells in eleven diverse settings representing sixty-seven experimental conditions. To better illustrate gene expression profiles in mouse ES cells, we have organized the results in an interactive database with a number of features and tools. Specifically, we have generated clusters of transcripts that behave the same way under the entire spectrum of the sixty-seven experimental conditions; we have assembled genes in groups according to their time of expression during successive days of ES cell differentiation; we have included expression profiles of specific gene classes such as transcription regulatory factors and Expressed Sequence Tags; transcripts have been arranged in "Expression Waves" and juxtaposed to genes with opposite or complementary expression patterns; we have designed search engines to display the expression profile of any transcript during ES cell differentiation; gene expression data have been organized in animated graphs of KEGG signaling and metabolic pathways; and finally, we have incorporated advanced functional annotations for individual genes or gene clusters of interest and links to microarray and genomic resources. The FunGenES database provides a comprehensive resource for studies into the biology of ES cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.