Evidence map›Paper›PMID 19726619›Full record

ArticleClinical and vaccine immunology : CVI2009

Simple and rapid lateral-flow assay for the detection of foot-and-mouth disease virus.

Jae Ku Oem, Nigel P Ferris, Kwang-Nyeong Lee, Yi-Seok Joo, Bang-Hun Hyun, Jong-Hyeon Park

Open access · diamondAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Foot-and-mouth disease in Asia.Virus research · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Advances in the Diagnosis of Foot-and-Mouth Disease.Frontiers in veterinary science · 2020
    Review
  8. Article
  9. Article
  10. Preparation and evaluation ofVeterinary world · 2017
    Article
  11. Article
  12. Novel foot-and-mouth disease virus in Korea, July-August 2014.Clinical and experimental vaccine research · 2016
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jae Ku OemNational Veterinary Research and Quarantine Service, Gyeonggi, Anyang, Anyang-6 dong 480, 430-757 Republic of Korea.
Nigel P Ferris
Kwang-Nyeong Lee
Yi-Seok Joo
Bang-Hun Hyun
Jong-Hyeon Park
National Veterinary Research and Quarantine Service · KRThe Pirbright Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A simple lateral-flow assay (LFA) based on a monoclonal antibody (MAb 70-17) was developed for the detection of foot-and-mouth disease virus (FMDV) under nonlaboratory conditions. The LFA was evaluated with epithelial suspensions (n = 704) prepared from current and historical field samples which had been submitted to the Pirbright Laboratory (United Kingdom) and from negative samples (n = 100) collected from naïve animals in Korea. Four FMDV serotypes (type O, A, Asia 1, and C) were detected in the LFA, but not the remaining three FMDV serotypes (SAT 1, SAT 2, and SAT 3). The diagnostic sensitivity of the LFA for FMDV types O, A, C, and Asia 1 was similar, at approximately 87.3%, to that of 87.7% obtained with antigen enzyme-linked immunosorbent assay (Ag-ELISA). The diagnostic specificity of the LFA was 98.8%, compared to 100% for the Ag-ELISA. These results demonstrate that the LFA using the FMDV MAb 70-17 to detect FMDV is a supportive method for taking rapid measurements at the site of a suspected foot-and-mouth disease outbreak in Asia before diagnosing the disease in the laboratory, thereby offering the possibility of implementing control procedures more rapidly.

Indexed as

Antibodies, MonoclonalAntibodies, ViralAnimalsFoot-and-Mouth DiseaseFoot-and-Mouth Disease VirusImmunoassayKoreaMiceMice, Inbred BALB CSensitivity and SpecificityUnited KingdomAntibodies, MonoclonalAntibodies, Viral

Identifiers

PMID19726619
PMCPMC2772383
OpenAlexW2122675991

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.