ArticleJournal of chromatography. B, Analytical technologies in the biomedical and life sciences2009
Leukotriene-E4 in human urine: Comparison of on-line purification and liquid chromatography-tandem mass spectrometry to affinity purification followed by enzyme immunoassay.
Article in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- Individualized therapy for persistent asthma in young children.The Journal of allergy and clinical immunology · 2016Trial
- Predictors of asthma control and lung function responsiveness to step 3 therapy in children with uncontrolled asthma.The Journal of allergy and clinical immunology · 2014Trial
- Urinary leukotriene E4/exhaled nitric oxide ratio and montelukast response in childhood asthma.The Journal of allergy and clinical immunology · 2010Trial
- Trial
- Multi-Omics Analysis of Lung Tissue Demonstrates Changes to Lipid Metabolism during Allergic Sensitization in Mice.Metabolites · 2023Article
- Profiling the oxylipidome in aged mice after chronic ethanol feeding: Identifying lipid metabolites as drivers of hepatocyte stress.Alcohol (Fayetteville, N.Y.) · 2023Article
- Lipid mediators are detectable in the nasal epithelium and differ by asthma status in female subjects.The Journal of allergy and clinical immunology · 2022Article
- Collection and Storage of Human Plasma for Measurement of Oxylipins.Metabolites · 2021Article
- Estimated time-varying exposures to air emissions from animal feeding operations and childhood asthma.International journal of hygiene and environmental health · 2020Article
- The Role of Leukotrienes as Potential Therapeutic Targets in Allergic Disorders.International journal of molecular sciences · 2019Review
- Quantitative metabolic profiling of urinary eicosanoids for clinical phenotyping.Journal of lipid research · 2019Article
- Evaluating lipid mediator structural complexity using ion mobility spectrometry combined with mass spectrometry.Bioanalysis · 2018Article
- Microbiome and metabolome data integration provides insight into health and disease.Translational research : the journal of laboratory and clinical medicine · 2017Review
- Within-microenvironment exposure to particulate matter and health effects in children with asthma: a pilot study utilizing real-time personal monitoring with GPS interface.Environmental health : a global access science source · 2016Article
- Hands-on workshops as an effective means of learning advanced technologies including genomics, proteomics and bioinformatics.Genomics, proteomics & bioinformatics · 2013Article
- Multiplexed analysis of steroid hormones in human serum using novel microflow tile technology and LC-MS/MS.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2013Article
- A simple and robust UPLC-SRM/MS method to quantify urinary eicosanoids.Journal of lipid research · 2012Article
- Urinary leukotriene E₄ levels identify children with tobacco smoke exposure at risk for asthma exacerbation.The Journal of allergy and clinical immunology · 2011Article
- Stable-isotope dilution LC–MS for quantitative biomarker analysis.Bioanalysis · 2010Review
- Analysis of endogenous glutathione-adducts and their metabolites.Biomedical chromatography : BMC · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
A new analytical method suitable for high throughput measurements of LTE(4) in human urine is described. The methodology utilizes on-line enrichment and liquid chromatography/tandem mass spectrometry (LC/MS/MS). The novel LC/MS/MS method is rapid, linear from 5 to 500pg/ml in spiked urine samples of both healthy and asthmatic subjects and more accurate and precise than enzyme immunoassay (EIA) and previous LC/MS/MS methods. Results from sample integrity experiments and preliminary values of urinary LTE(4) from healthy adults and children are reported.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.