ArticleHereditary cancer in clinical practice2007
A short guide to hereditary diffuse gastric cancer.
Article in Hereditary cancer in clinical practice, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 50 citations in OpenAlex.
- Linking CDH1 SNPs to gastric cancer risk: a comprehensive analysis of rs16260, rs13689, and rs9929218.Molecular biology reports · 2024Article
- Mutational landscape of TP53 and CDH1 in gastric cancer.World journal of gastrointestinal surgery · 2024Article
- Current advances in understanding the molecular profile of hereditary diffuse gastric cancer and its clinical implications.Journal of experimental & clinical cancer research : CR · 2023Review
- Identification of hub pathways and drug candidates in gastric cancer through systems biology.Scientific reports · 2022Article
- Gastric Cancer: Epidemiology, Risk Factors, Classification, Genomic Characteristics and Treatment Strategies.International journal of molecular sciences · 2020Review
- Significance of Detection of the HER2 Gene and PD-1/PD-L1 in Gastric Cancer.Journal of oncology · 2020Article
- CDH1 (E-Cadherin) Mutation and Gastric Cancer: Genetics, Molecular Mechanisms and Guidelines for Management.Cancer management and research · 2019Review
- Germline pathogenic variants in PALB2 and other cancer-predisposing genes in families with hereditary diffuse gastric cancer without CDH1 mutation: a whole-exome sequencing study.The lancet. Gastroenterology & hepatology · 2018Article
- Inherited Cancer in the Age of Next-Generation Sequencing.Biological research for nursing · 2018Review
- Comparative study of endoscopic surveillance in hereditary diffuse gastric cancer according to CDH1 mutation status.Gastrointestinal endoscopy · 2018Article
- CDH1 Gene and Hereditary Diffuse Gastric Cancer Syndrome: Molecular and Histological Alterations and Implications for Diagnosis And Treatment.Frontiers in pharmacology · 2018Review
- Genetic screening analysis of patients with hereditary diffuse gastric cancer from northern and northeastern Brazil.Hereditary cancer in clinical practice · 2014Article
- Gastric cáncer: Overview.Colombia medica (Cali, Colombia) · 2013Review
- Article
- Prevention is better than cure.Journal of surgical case reports · 2012Article
- Polymorphisms in the 3'-untranslated region of the CDH1 gene are a risk factor for primary gastric diffuse large B-cell lymphoma.Haematologica · 2011Article
- CDH1 gene mutations do not contribute in hereditary diffuse gastric cancer in Poland.Familial cancer · 2010Article
- Increased levels of active c-Src distinguish invasive from in situ lobular lesions.Breast cancer research : BCR · 2009Article
- Hereditary diffuse gastric cancer: prophylactic surgical oncology implications.The Surgical clinics of North America · 2008Review
- A novel diffuse gastric cancer susceptibility variant in E-cadherin (CDH1) intron 2: a case control study in an Italian population.BMC cancer · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hereditary diffuse gastric cancer (HDGC) is the only known predisposition syndrome dominated by carcinoma of the stomach and with a recognised genetic cause. Germline mutations in the E-cadherin gene (CDH1) co-segregate with the disease in about half of the families with multiple diffuse gastric cancer. In these families, identification of the CDH1 mutation allows for clinical measures to be taken. Importantly, clinical intervention is likely to be therapeutic and associated with tolerable morbidity. This review is thus aimed at providing a current overview of the clinical management and the underlying biology of HDGC.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.