Evidence map›Paper›PMID 19725934›Full record

ReviewJournal of biology2009

Insulators as mediators of intra- and inter-chromosomal interactions: a common evolutionary theme.

Chin-Tong Ong, Victor G Corces

Open access · goldAbstract readReview
In one paragraph

Review in Journal of biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Chin-Tong OngDepartment of Biology, Emory University, 1510 Clifton Road NE, Atlanta, GA 30322, USA.
Victor G Corces
Emory University · US

Funding

MOLECULAR BASIS OF SUPPRESSION IN DROSOPHILAR01GM035463 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI CORCES, VICTOR G. · 1986 to 2020
$10.7M
NIGMS NIH HHS GM35463NIGMS NIH HHS R01 GM035463
6 · The paper itself

Abstract

Insulator elements mediate intra- and inter-chromosomal interactions. The insulator protein CCCTC-binding factor (CTCF) is important for insulator function in several animals but a report in BMC Molecular Biology shows that Caenorhabditis elegans, yeast and plants lack CTCF. Alternative proteins may have a similar function in these organisms.

Indexed as

Evolution, MolecularInsulator ElementsAnimalsCCCTC-Binding FactorChromosomesGene Expression RegulationGenomeHumansRepressor ProteinsCCCTC-Binding FactorCTCF protein, humanRepressor Proteins

Identifiers

PMID19725934
PMCPMC2776911
OpenAlexW2149485133

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.