Trial reportSleep2009
Diclofenac potassium restores objective and subjective measures of sleep quality in women with primary dysmenorrhea.
Trial report in Sleep, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 60 citations in OpenAlex.
- Uncovering Sleep Behaviour in Women's Football: What Evidence Do We Have?Sports medicine (Auckland, N.Z.) · 2026Review
- Psychosocial Predictors of Dysmenorrhea Stability and Change: A Two-Year Longitudinal Study.Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC · 2026Article
- Exploring predictors of analgesic response in adult women regularly using NSAIDs: insights from a machine learning approach.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Whole-body cryostimulation exposures effectively alleviates menstrual-related pain and associated sleep disturbances in young women: a randomized controlled trial.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- Altered sleep and diurnal consequences in women with dysmenorrhea: study from the EPISONO database.Archives of gynecology and obstetrics · 2024Article
- Article
- The Menstrual Cycle and Sleep.Sleep medicine clinics · 2023Review
- Scientific Knowledge Graph of Dysmenorrhea: A Bibliometric Analysis from 2001 to 2021.Journal of pain research · 2023Article
- Sleep quality of adult psychiatric outpatients at Chris Hani Baragwanath Academic Hospital.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2023Article
- 24-hour urinary potassium excretion is negatively associated with self-reported sleep quality in the general population, independently of sleep-disordered breathing.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- "Tomorrow, I'll Be Fine": Impacts and coping mechanisms in adolescents and young adults with primary dysmenorrhoea.Journal of advanced nursing · 2020Article
- Comparison of the effects of acupressure and self-care behaviors training on the intensity of primary dysmenorrhea based on McGill pain questionnaire among Shiraz University students.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2016Article
- Effects of wheat germ extract on the severity and systemic symptoms of primary dysmenorrhea: a randomized controlled clinical trial.Iranian Red Crescent medical journal · 2014Article
- Weighing the balance: how analgesics used in chronic pain influence sleep?British journal of pain · 2014Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesPrimary dysmenorrhea is a common gynecological disorder that disrupts daytime functioning and nighttime sleep quality. We determined the effectiveness of diclofenac potassium, compared to placebo, in alleviating nighttime pain and restoring sleep architecture in women with primary dysmenorrhea.
designRandomized, double-blind, crossover study.
settingSleep laboratory.
participantsTen healthy women (21 +/- 1 years) with a history of primary dysmenorrhea.
interventionsPlacebo or diclofenac potassium (150 mg per day) for menstrual pain. MEASUREMENTS AND
resultsWe assessed objective measures of sleep (polysomnography) and subjective measures of sleep quality, mood, and intensity of menstrual pain. Compared to a pain-free phase of the menstrual cycle (mid-follicular), women receiving placebo for their menstrual pain had a poorer mood (P < 0.01), decreased sleep efficiency (P < 0.05), less REM sleep (P < 0.05), more stage 1 sleep (P < 0.01), and more sleep stage changes per hour of sleep during the night. Administration of diclofenac potassium compared to placebo not only attenuated the women's menstrual pain (P < 0.05), but also increased sleep efficiency (P < 0.05) and percentage of REM sleep (P < 0.01), decreased percentage of stage 1 sleep (P < 0.05) and number of sleep stage changes per hour of sleep (P < 0.05), and improved subjective ratings of sleep quality and morning vigilance (P < 0.05).
conclusionDiclofenac potassium effectively attenuates nighttime dysmenorrheic pain and restores subjective and objective measures of sleep quality to values recorded in a pain-free phase of the menstrual cycle.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.