ArticleGenes & development2009
Regulating the regulator: an RNA decoy acts as an OFF switch for the regulation of an sRNA.
Article in Genes & development, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- A Small RNA Derived From the 5' End of the IS200 tnpA Transcript Regulates Multiple Virulence Regulons in Salmonella typhimurium.Molecular microbiology · 2025Article
- What goes up must come down: off switches for regulatory RNAs.Genes & development · 2024Review
- PhoP induces RyjB expression under acid stress in Escherichia coli.Journal of biochemistry · 2022Article
- sRNA-mediated RNA processing regulates bacterial cell division.Nucleic acids research · 2021Article
- C-terminal domain of the RNA chaperone Hfq drives sRNA competition and release of target RNA.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Article
- Cross talk between ABC transporter mRNAs via a target mRNA-derived sponge of the GcvB small RNA.The EMBO journal · 2015Article
- Small RNA functions in carbon metabolism and virulence of enteric pathogens.Frontiers in cellular and infection microbiology · 2014Review
- Competing endogenous RNAs (ceRNAs): new entrants to the intricacies of gene regulation.Frontiers in genetics · 2014Review
- A novel CsrA titration mechanism regulates fimbrial gene expression in Salmonella typhimurium.The EMBO journal · 2013Article
- Structural insights into the dynamics and function of the C-terminus of the E. coli RNA chaperone Hfq.Nucleic acids research · 2011Article
- Emerging roles for natural microRNA sponges.Current biology : CB · 2010Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Many bacterial small regulatory RNAs (sRNAs) pair with mRNA targets, stimulating or inhibiting mRNA stability and/or translation. Regulation of these sRNAs is usually due to tight transcriptional regulation of synthesis.In this issue of Genes & Development and a related paper in Molecular Microbiology, Figueroa-Bossi and colleagues (pp. 2004-2015) and Overgaard and colleagues report a novel regulatory mechanism in which induction of a competing mRNA acts to titrate away the sRNA, allowing expression of an otherwise strongly inhibited target gene.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.