ArticleCurrent osteoporosis reports2009
From relative risk to absolute fracture risk calculation: the FRAX algorithm.
Article in Current osteoporosis reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Impact of femoral neck and lumbar spine BMD discordances on FRAX probabilities in women: a meta-analysis of international cohorts.Calcified tissue international · 2014Pooled it
- 2015 Guidelines for Osteoporosis in Saudi Arabia: Recommendations from the Saudi Osteoporosis Society.Annals of Saudi medicineGuideline
- Randomized controlled trial of vitamin D supplementation in older people to optimize bone health.The American journal of clinical nutrition · 2019Trial
- Trial
- Article
- Laboratory-based Biomarkers for Risk Prediction, Auxiliary Diagnosis and Post-operative Follow-up of Osteoporotic Fractures.Current osteoporosis reports · 2025Review
- Treatment reclassification in Canada from the Osteoporosis Canada 2023 clinical practice guidelines: the Manitoba BMD Registry.Archives of osteoporosis · 2024Article
- Enhanced osteoporotic fracture prediction in postmenopausal women using Bayesian optimization of machine learning models with genetic risk score.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024Article
- Nutraceuticals in osteoporosis prevention.Frontiers in nutrition · 2024Review
- Dietary acrylamide and incident osteoporotic fractures: an 8-year prospective cohort study.Aging clinical and experimental research · 2022Article
- Factors associated with initiation of bone-health medication among older adults in primary care in Ireland.Age and ageing · 2021Article
- Bone Health in Idiopathic Inflammatory Myopathies: Diagnosis and Management.Current rheumatology reports · 2021Review
- [Risk assessment in osteoporosis : Time-tested and new approaches].Der Internist · 2021Review
- Analytical considerations and plans to standardize or harmonize assays for the reference bone turnover markers PINP and β-CTX in blood.Clinica chimica acta; international journal of clinical chemistry · 2021Article
- Machine Learning Approaches for Fracture Risk Assessment: A Comparative Analysis of Genomic and Phenotypic Data in 5130 Older Men.Calcified tissue international · 2020Article
- Lung-Specific Risk Factors Associated With Incident Hip Fracture in Current and Former Smokers.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2020Observational
- Article
- Discovery of potential biomarkers for osteoporosis using LC-MS/MS metabolomic methods.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019Article
- Primary care physicians' views on osteoporosis management: a qualitative study.Archives of osteoporosis · 2019Article
- The impact of low-dose glucocorticoids on disease activity, bone mineral density, fragility fractures, and 10-year probability of fractures in patients with rheumatoid arthritis.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
FRAX is a computer-based algorithm that provides models for the assessment of fracture probability in men and women (http://www.shef.ac.uk/FRAX). The approach uses easily obtained clinical risk factors to estimate 10-year fracture probability, with or without femoral neck bone mineral density (BMD), to enhance fracture risk prediction. It has been constructed using primary data from population-based cohorts around the world. The gradients of fracture risk have been validated in independent cohorts with a similar geographic distribution. The FRAX tool should not be considered as a gold standard, but rather as a platform technology on which to build as new validated risk indicators become available. Notwithstanding, the present models provide an aid to enhance patient assessment by the integration of clinical risk factors alone and/or in combination with BMD. This article describes the steps undertaken in the development of FRAX.
Indexed as
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19723465What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.