Evidence map›Paper›PMID 19723406›Full record

ArticleThe international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease2009

Prevalence and risk factors for drug resistance among hospitalized tuberculosis patients in Georgia.

L Vashakidze, A Salakaia, N Shubladze, M Cynamon, K Barbakadze, M Kikvidze, L Papitashvili, M Nonikashvili, N Solomonia, N Bejanishvili and 1 more

Open access · greenAbstract read
In one paragraph

Article in The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Epidemiology of extensively drug-resistant tuberculosis among patients with multidrug-resistant tuberculosis: A systematic review and meta-analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023
    Pooled it
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  6. Prevalence and Factors Associated with Multidrug-Resistant Tuberculosis (MDR-TB) among Presumptive MDR-TB Patients in Tigray Region, Northern Ethiopia.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2019
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  10. Geographical heterogeneity of multidrug-resistant tuberculosis in Georgia, January 2009 to June 2011.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2014
    Article
  11. Article
  12. Molecular patterns of multidrug resistance ofInternational journal of mycobacteriology · 2013
    Article
  13. Outcomes of children treated for tuberculosis with second-line medications in Georgia, 2009-2011.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2013
    Article
  14. Prescribed and self-medication use increase delays in diagnosis of tuberculosis in the country of Georgia.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2013
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

L VashakidzeNational Centre for Tuberculosis and Lung Diseases, Tbilisi, Georgia.
A Salakaia
N Shubladze
M Cynamon
K Barbakadze
M Kikvidze
L Papitashvili
M Nonikashvili
N Solomonia
N Bejanishvili
I Khurtsilava
National Center for Tuberculosis and Lung Disease · GE

Funding

Emory-Georgia TB Research Training ProgramD43TW007124 · FIC · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Nestani Tukvadze · 2004 to 2026
$4.6M
FIC NIH HHS D43 TW007124
6 · The paper itself

Abstract

backgroundTuberculosis (TB) control in Georgia follows the World Health Organization-recommended DOTS strategy, and has reached global TB control targets in the treatment of susceptible TB; however, the management of drug-resistant forms of TB still represents a serious problem. A countrywide drug resistance survey (DRS) found that the prevalence of multidrug-resistant TB (MDR-TB) was respectively 6.8% and 27.4% in new and previously treated TB cases.

objectiveTo determine the prevalence of and risk factors for drug resistance among TB patients to improve case management and control of drug-resistant TB.

methodsExtensive social, clinical and bacteriological data were collected from patients hospitalized at the National Centre for Tuberculosis and Lung Diseases, Georgia, between 2005 and 2007.

resultsOf 605 patients, resistance was observed in 491 (81.2%); MDR-TB was found in 261 (43.1%; 51/222 [23%] new cases and 210/383 [55%] previously treated cases), monoresistant TB in 130 (21.5%), poly-resistant TB in 67 (11.1%) and extensively drug-resistant TB in 33 (5.5%). Female sex, living in the densely populated capital, family TB contact and previous TB treatment were associated with risk of MDR-TB.

conclusionsThese findings confirm the necessity of improving infection control measures and of standardized treatment for drug-resistant TB patients.

Indexed as

Drug Resistance, Multiple, BacterialAdultAntitubercular AgentsBacteriological TechniquesCross-Sectional StudiesFemaleGeorgia (Republic)HumansInfection ControlInpatientsLogistic ModelsMaleMiddle AgedMycobacterium tuberculosisOdds RatioPopulation DensityAntitubercular Agents

Identifiers

PMID19723406
PMCPMC2935085
OpenAlexW70832381

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.