Evidence map›Paper›PMID 19722838›Full record

ReviewFuture microbiology2009

A structural and functional perspective of alphavirus replication and assembly.

Joyce Jose, Jonathan E Snyder, Richard J Kuhn

Open access · greenAbstract readReview
In one paragraph

Review in Future microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 224 papers.

0numbers the graph read from it
0cells of the map it votes in
224citing papers in PubMed
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

224 citing papers in PubMed, 394 citations in OpenAlex.

  1. Review
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  12. Getah Virus in Review: An Emerging Zoonotic Arbovirus.Transboundary and emerging diseases · 2026
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Ion-Channel-Targeting Drugs for Chikungunya Virus.Molecules (Basel, Switzerland) · 2025
    Article
  19. Article
  20. Article

164 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Joyce JoseDepartment of Biological Sciences, Bindley Bioscience Center, Lilly Hall of Life Sciences, 915 West State St., Purdue University, West Lafayette, IN 47907, USA. jjose@purdue.edu
Jonathan E Snyder
Richard J Kuhn
Purdue University West Lafayette · US

Funding

MOLECULAR BASIS OF ALPHAVIRUS ASSEMBLYR01GM056279 · NIGMS · PURDUE UNIVERSITY WEST LAFAYETTE · PI KUHN, RICHARD J. · 1997 to 2014
$3.7M
NIGMS NIH HHS GM56279NIGMS NIH HHS R01 GM056279
6 · The paper itself

Abstract

Alphaviruses are small, spherical, enveloped, positive-sense ssRNA viruses responsible for a considerable number of human and animal diseases. Alphavirus members include Chikungunya virus, Sindbis virus, Semliki Forest virus, the western, eastern and Venezuelan equine encephalitis viruses, and the Ross River virus. Alphaviruses can cause arthritic diseases and encephalitis in humans and animals and continue to be a worldwide threat. The viruses are transmitted by blood-sucking arthropods, and replicate in both arthropod and vertebrate hosts. Alphaviruses form spherical particles (65-70 nm in diameter) with icosahedral symmetry and a triangulation number of four. The icosahedral structures of alphaviruses have been defined to very high resolutions by cryo-electron microscopy and crystallographic studies. In this review, we summarize the major events in alphavirus infection: entry, replication, assembly and budding. We focus on data acquired from structural and functional studies of the alphaviruses. These structural and functional data provide a broader perspective of the virus lifecycle and structure, and allow additional insight into these important viruses.

Indexed as

Virus AssemblyVirus InternalizationVirus ReplicationAlphavirusModels, BiologicalModels, MolecularViral ProteinsVirionViral Proteins

Identifiers

PMID19722838
PMCPMC2762864
OpenAlexW1991353963

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.