Evidence map›Paper›PMID 19720865›Full record

ArticleAmerican journal of epidemiology2009

Gender-specific associations between soy and risk of hip fracture in the Singapore Chinese Health Study.

Woon-Puay Koh, Anna H Wu, Renwei Wang, Li-Wei Ang, Derrick Heng, Jian-Min Yuan, Mimi C Yu

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of epidemiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 10 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 10 syntheses or guidelines pooled it, 95 citations in OpenAlex.

  1. Gender differences between smoking and the risk of hip fracture.Journal of bone and mineral metabolism · 2024
    Pooled it
  2. Update of the fracture risk prediction tool FRAX: a systematic review of potential cohorts and analysis plan.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
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  9. Alcohol consumption and hip fracture risk.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Woon-Puay KohDepartment of Epidemiology and Public Health, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. ephkwp@nus.edu.sg
Anna H Wu
Renwei Wang
Li-Wei Ang
Derrick Heng
Jian-Min Yuan
Mimi C Yu
National University of Singapore · SG

Funding

THE SINGAPORE COHORT STUDY OF DIET AND CANCERR01CA080205 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI YUAN, JIAN-MIN · 1999 to 2009
$5.3M
COHORT STUDY OF DIET AND NASOPHYARYNGEAL CANCERR01CA055069 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI YU, MIMI C. · 1992 to 1992
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ENVIRONMENTAL EXPOSURES IN CANCER ETIOLOGYR35CA053890 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI YU, MIMI C. · 1992 to 1998
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NCI NIH HHS R01 CA055069NCI NIH HHS R01 CA080205NCI NIH HHS R01 CA80205NCI NIH HHS R35 CA053890
6 · The paper itself

Abstract

Although there is some epidemiologic evidence that soy may reduce risk of osteoporotic fracture in women, it is not known whether this risk reduction also occurs for men. The authors examined gender-specific associations between soy intake and hip fracture risk in the Singapore Chinese Health Study, a prospective cohort of 63,257 Chinese living in Singapore. At recruitment between 1993 and 1998, each subject was administered a food frequency questionnaire and questions on medical history and lifestyle factors. As of December 31, 2006, 276 incident cases of hip fracture in men and 692 cases in women were identified via linkage with hospital discharge databases. For both genders, hip fracture risk was positively associated with cigarette smoking and was inversely associated with body mass index. There was a statistically significant association of tofu equivalents, soy protein, and isoflavones with hip fracture risk among women but not among men. Compared with women in the lowest quartile of intakes for tofu equivalents (<49.4 g/day), soy protein (<2.7 g/day), and isoflavones (<5.8 mg/1,000 kcal/day), those in the second-fourth quartiles exhibited 21%-36% reductions in risk (all P < 0.036). Risk levels were comparable across the second, third, and fourth quartiles of soy intake categories.

Indexed as

Asian PeopleSoy FoodsAgedChinaDietFemaleHip FracturesHumansIncidenceIsoflavonesMaleMiddle AgedOsteoporosisProspective StudiesRisk FactorsSex DistributionIsoflavones

Identifiers

PMID19720865
PMCPMC2765361
OpenAlexW2124494239

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.