ArticleJournal of medicinal chemistry2009
Amide isosteres of oroidin: assessment of antibiofilm activity and C. elegans toxicity.
Article in Journal of medicinal chemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Antimicrobial Activity of Naturally Occurring Phenols and Derivatives Against Biofilm and Planktonic Bacteria.Frontiers in chemistry · 2019Article
- 2-Aminobenzimidazoles as antibiofilm agents againstMedChemComm · 2018Article
- 5-Benzylidene-4-oxazolidinones potently inhibit biofilm formation in Methicillin-resistant Staphylococcus aureus.Chemical communications (Cambridge, England) · 2017Article
- Marine sponge alkaloids as a source of anti-bacterial adjuvants.Bioorganic & medicinal chemistry letters · 2016Article
- Going beyond the Control of Quorum-Sensing to Combat Biofilm Infections.Antibiotics (Basel, Switzerland) · 2016Review
- A Pipeline for Screening Small Molecules with Growth Inhibitory Activity against Burkholderia cenocepacia.PloS one · 2015Article
- The bromotyrosine derivative ianthelline isolated from the arctic marine sponge Stryphnus fortis inhibits marine micro- and macrobiofouling.Marine biotechnology (New York, N.Y.) · 2014Article
- Antimicrobial activity of the marine alkaloids, clathrodin and oroidin, and their synthetic analogues.Marine drugs · 2014Article
- Identification of BfmR, a response regulator involved in biofilm development, as a target for a 2-Aminoimidazole-based antibiofilm agent.Biochemistry · 2012Article
- Evaluation of the toxicity of 2-aminoimidazole antibiofilm agents using both cellular and model organism systems.Drug and chemical toxicology · 2012Article
- Novel pentadecenyl tetrazole enhances susceptibility of methicillin-resistant Staphylococcus aureus biofilms to gentamicin.Antimicrobial agents and chemotherapy · 2011Article
- Anti-biofilm compounds derived from marine sponges.Marine drugs · 2011Review
- Combining Biofilm-Controlling Compounds and Antibiotics as a Promising New Way to Control Biofilm Infections.Pharmaceuticals (Basel, Switzerland) · 2010Review
- Synergistic effects between conventional antibiotics and 2-aminoimidazole-derived antibiofilm agents.Antimicrobial agents and chemotherapy · 2010Article
- A submarine journey: the pyrrole-imidazole alkaloids.Marine drugs · 2009Review
- Inhibition and breaking of advanced glycation end-products (AGEs) with bis-2-aminoimidazole derivatives.Tetrahedron lettersArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
The synthesis and antibiofilm activities of sulfonamide, urea, and thiourea oroidin analogues are described. The most active derivative was able to selectively inhibit P. aeruginosa biofilm development and is also shown to be nontoxic upward of 1 mM to the development of C. elegans in comparison to other similar isosteric analogues and the natural product oroidin.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.