ArticleJournal of the American Medical Informatics Association : JAMIA
Translating clinical informatics interventions into routine clinical care: how can the RE-AIM framework help?
Article in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Deployment of machine learning algorithms to predict sepsis: systematic review and application of the SALIENT clinical AI implementation framework.Journal of the American Medical Informatics Association : JAMIA · 2023Pooled it
- Fidelity to and comparative results across behavioral interventions evaluated through the RE-AIM framework: a systematic review.Systematic reviews · 2015Pooled it
- Implementing 360° Quantified Self for childhood obesity: feasibility study and experiences from a weight loss camp in Qatar.BMC medical informatics and decision making · 2017Trial
- Design and implementation of electronic health record integrated clinical prediction rules (iCPR): a randomized trial in diverse primary care settings.Implementation science : IS · 2017Trial
- Implementation of the Tobacco Tactics intervention versus usual care in Trinity Health community hospitals.Implementation science : IS · 2016Trial
- Engaging hospitalized patients in clinical care: Study protocol for a pragmatic randomized controlled trial.Contemporary clinical trials · 2016Trial
- Noninvasive image texture analysis differentiates K-ras mutation from pan-wildtype NSCLC and is prognostic.PloS one · 2014Trial
- Avoiding "shiny objects" and heeding "red flags": a sensemaking framework for emerging technology procurement.JAMIA open · 2026Article
- Institutionalizing Digital Parenting Programs in Low Resource Settings in China: Comparative Case Study of Health Care and Education Sectors Using the RE-AIM Framework.Journal of medical Internet research · 2026Article
- Assessing Clinical Impressions of Early Warning Score Integration With the Rapid Response Team: Protocol for a Prospective Cohort Study.JMIR research protocols · 2025Article
- Overcoming inertia: Provider perspectives on de-implementation strategies in preoperative testing.American journal of surgery · 2025Article
- The Symphony of Consumer Partnering and Clinical Governance: An Organizational Review Using the RE-AIM Framework.Health expectations : an international journal of public participation in health care and health policy · 2024Article
- A scoping review, novel taxonomy and catalogue of implementation frameworks for clinical decision support systems.BMC medical informatics and decision making · 2024Article
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- Identifying Facilitators and Barriers to Implementation of AI-Assisted Clinical Decision Support in an Electronic Health Record System.Journal of medical systems · 2024Article
- Article
- Use of artificial intelligence in critical care: opportunities and obstacles.Critical care (London, England) · 2024Review
- Implementation of remote home care: assessment guided by the RE-AIM framework.BMC health services research · 2024Article
- Blended-ALMAMAR app for inpatient mental health care for refugees: study protocol for a multicenter implementation study within the I-REACH consortium (Internet based REfugee mentAl healtH Care).BMC health services research · 2023Article
- Celebrating Suzanne Bakken, 2023 Morris F. Collen Award winner and pioneer in health equity.Journal of the American Medical Informatics Association : JAMIA · 2023Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
objectiveClinical informatics intervention research suffers from a lack of attention to external validity in study design, implementation, evaluation, and reporting. This hampers the ability of others to assess the fit of a clinical informatics intervention with demonstrated efficacy in one setting for implementation in their setting. The objective of this model formulation paper is to demonstrate the applicability of the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework with proposed extensions to clinical informatics intervention research and describe the framework's role in facilitating the translation of evidence into practice and generation of evidence from practice. Both aspects are essential to reap the clinical and public health benefits of clinical informatics research.
designWe expanded RE-AIM through the addition of assessment questions relevant to clinical informatics intervention research including those related to predisposing, enabling, and reinforcing factors and validated it with two case studies.
resultsThe first case study supported the applicability of RE-AIM to inform real world implementation of a clinical informatics intervention with demonstrated efficacy in randomized controlled trials (RCTs)--the Choice (Creating better Health Outcomes by Improving Communication about Patients' Experiences) intervention. The second, an RCT of a personal digital assistant-based decision support system for guideline-based care, illustrated how RE-AIM can be used to inform the design of an efficacy RCT that captures essential contextual details typically lacking in RCT design and reporting.
conclusionThe case studies validate, through example, the applicability of RE-AIM to inform the design, implementation, evaluation, and reporting of clinical informatics intervention studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.