Evidence map›Paper›PMID 19717739›Full record

ArticleEukaryotic cell2009

Neurofibromin homologs Ira1 and Ira2 affect glycerophosphoinositol production and transport in Saccharomyces cerevisiae.

Andrew C Bishop, Beth A Surlow, Puneet Anand, Katherine Hofer, Matthew Henkel, Jana Patton-Vogt

Open access · diamondAbstract read
In one paragraph

Article in Eukaryotic cell, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Andrew C BishopDepartment of Biological Sciences, Duquesne University, Pittsburgh, PA 15282, USA.
Beth A Surlow
Puneet Anand
Katherine Hofer
Matthew Henkel
Jana Patton-Vogt
Duquesne University · US

Funding

REGULATION OF GLYCEROPHOSPHOINOSITOL TRANSPORT IN YEASTR01GM059817 · NIGMS · DUQUESNE UNIVERSITY · PI VOGT, JANA L · 2001 to 2006
$1.1M
NIGMS NIH HHS GM59817NIGMS NIH HHS R01 GM059817
6 · The paper itself

Abstract

Saccharomyces cerevisiae produces extracellular glycerophosphoinositol through phospholipase-mediated turnover of phosphatidylinositol and transports glycerophosphoinositol into the cell upon nutrient limitation. A screening identified the RAS GTPase-activating proteins Ira1 and Ira2 as required for utilization of glycerophosphoinositol as the sole phosphate source, but the RAS/cyclic AMP pathway does not appear to be involved in the growth phenotype. Ira1 and Ira2 affect both the production and transport of glycerophosphoinositol.

Indexed as

Biological TransportGTPase-Activating ProteinsInositol PhosphatesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsglycerylphosphoinositolGTPase-Activating ProteinsInositol PhosphatesIRA1 protein, S cerevisiaeIRA2 protein, S cerevisiaeSaccharomyces cerevisiae Proteins

Identifiers

PMID19717739
PMCPMC2772407
OpenAlexW2100951416

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.