ArticleJournal of medical ethics2009
Ethics and methods in surgical trials.
Article in Journal of medical ethics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Prominent Literature in Surgical Ethics: A Comprehensive Bibliometric Analysis of the Top 50 Most-Cited Articles.Cureus · 2025Review
- Innovative Bariatric Procedures and Ethics in Bariatric Surgery: the IFSO Position Statement.Obesity surgery · 2022Article
- Lack of predictive tools for conventional and targeted cancer therapy: Barriers to biomarker development and clinical translation.Advanced drug delivery reviews · 2021Review
- Statistical Basic Steps to Be Considered on Planning a Research.Plastic and reconstructive surgery. Global open · 2018Article
- Designing clinical trials in trauma surgery: overcoming research barriers.Bone & joint research · 2014Article
- Are surgical trials with negative results being interpreted correctly?Journal of the American College of Surgeons · 2013Article
- Trials and tribulations: the professional development of surgical trialists.American journal of surgery · 2012Article
- Conflicts among multinational ethical and scientific standards for clinical trials of therapeutic interventions.The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2012Article
- A taxonomy of multinational ethical and methodological standards for clinical trials of therapeutic interventions.Journal of medical ethics · 2011Article
- Ethical issues in surgical trials and in the diffusion of innovative therapies.Texas Heart Institute journal · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
This paper focuses on invasive therapeutic procedures, defined as procedures requiring the introduction of hands, instruments, or devices into the body via incisions or punctures of the skin or mucous membranes performed with the intent of changing the natural history of a human disease or condition for the better. Ethical and methodological concerns have been expressed about studies designed to evaluate the effects of invasive therapeutic procedures. Can such studies meet the same standards demanded of those, for example, evaluating pharmaceutical agents? This paper describes a research project aimed at examining the interplay and sometimes apparent conflict between ethical standards for human research and standards for methodological rigor in trials of invasive procedures. The paper discusses how the authors plan to develop a set of consensus standards that, if met, would result in substantial and much-needed improvements in the methodological and ethical quality of such trials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.