ArticleThe Plant cell2009
The trihelix transcription factor GTL1 regulates ploidy-dependent cell growth in the Arabidopsis trichome.
Article in The Plant cell, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
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Who cites it
56 citing papers in PubMed, 109 citations in OpenAlex.
- Molecular regulation of plant endoreduplication: core mechanisms and their upstream control.Plant molecular biology · 2026Review
- Comprehensive insights into the development of arabidopsis trichomes by single-nucleus RNA-seq.BMC plant biology · 2026Article
- Trihelix transcription factors: versatile regulators in plant growth and development, abiotic, and biotic stress responses.Plant cell reports · 2026Review
- Genome-wide identification of potato Trihelix gene family and its response to different abiotic stresses.BMC plant biology · 2025Article
- Salicylic acid accumulation: emerging molecular players and novel perspectives on plant development and nutrition.Journal of experimental botany · 2025Review
- Trihelix Transcription Factor OsTGS1 Regulates Grain Size and Weight in Rice.Rice (New York, N.Y.) · 2025Article
- Trichome development of systemic developing leaves is regulated by a nutrient sensor-relay mechanism within mature leaves.Science advances · 2025Article
- Red peel regulator 1 links ethylene response factor 25 and β-citraurin biosynthetic genes to regulate ethylene-induced peel reddening in citrus.The Plant cell · 2024Article
- Genome-Wide Identification of the Trihelix Transcription Factor Family and Functional Analysis ofInternational journal of molecular sciences · 2024Article
- New insights into the evolution analysis of trihelix gene family in eggplant (Solanum melongena L.) and expression analysis under abiotic stress.BMC genomics · 2024Article
- Transcriptional repression ofPlant direct · 2024Article
- Genome-wide identification and expression analysis of the Trihelix transcription factor family in potato (PeerJ · 2024Article
- Genome-wide expression analysis ofPlant signaling & behavior · 2023Article
- Comprehensive Genomic Analysis of Trihelix Family in Tea Plant (Plants (Basel, Switzerland) · 2023Article
- Deciphering the Mechanism of Tolerance to Apple Replant Disease Using a Genetic Mapping Approach in a Malling 9 ×International journal of molecular sciences · 2023Article
- Genome-wide characterization and identification of Trihelix transcription factors and expression profiling in response to abiotic stresses in Chinese Willow (Frontiers in plant science · 2023Article
- Conservation and Divergence of the Trihelix Genes in Brassica and Expression Profiles ofInternational journal of molecular sciences · 2022Article
- Trihelix transcription factors GTL1 and DF1 prevent aberrant root hair formation in an excess nutrient condition.The New phytologist · 2022Article
- Altered Developmental and Metabolic Gene Expression in Basil Interspecific Hybrids.Plants (Basel, Switzerland) · 2022Article
- Molecular Mechanisms of Plant Trichome Development.Frontiers in plant science · 2022Review
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leaf trichomes in Arabidopsis thaliana develop through several distinct cellular processes, such as patterning, differentiation, and growth. Although recent studies have identified several key transcription factors as regulating early patterning and differentiation steps, it is still largely unknown how these regulatory proteins mediate subsequent trichome development, which is accompanied by rapid cell growth and branching. Here, we report a novel trichome mutation in Arabidopsis, which in contrast with previously identified mutants, increases trichome cell size without altering its overall patterning or branching. We show that the corresponding gene encodes a GT-2-LIKE1 (GTL1) protein, a member of the trihelix transcription factor family. GTL1 is present within the nucleus during the postbranching stages of trichome development, and its loss of function leads to an increase in the nuclear DNA content only in trichomes that have completed branching. Our data further demonstrate that the gtl1 mutation modifies the expression of several cell cycle genes and partially rescues the ploidy defects in the cyclin-dependent kinase inhibitor mutant siamese. Taken together, this study provides the genetic evidence for the requirement of transcriptional regulation in the repression of ploidy-dependent plant cell growth as well as for an involvement of GTL trihelix proteins in this regulation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.