ArticleJournal of bacteriology2009
Bacillus subtilis SpoIIIJ and YqjG function in membrane protein biogenesis.
Article in Journal of bacteriology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 45 citations in OpenAlex.
- A lipid cue drives the subcellular localization of a self-inserting bacterial transmembrane protein.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- A lipid cue drives the subcellular localization of a self-inserting bacterial transmembrane protein.bioRxiv : the preprint server for biology · 2026Article
- Nucleic acid-binding KH domain proteins influence a spectrum of biological pathways including as part of membrane-localized complexes.Journal of structural biology: X · 2024Article
- Mutations of the Bacillus subtilis YidC1 (SpoIIIJ) insertase alleviate stress associated with σM-dependent membrane protein overproduction.PLoS genetics · 2019Article
- The interaction network of the YidC insertase with the SecYEG translocon, SRP and the SRP receptor FtsY.Scientific reports · 2018Article
- The Blueprint of a Minimal Cell: MiniBacillus.Microbiology and molecular biology reviews : MMBR · 2016Review
- The Escherichia coli membrane protein insertase YidC assists in the biogenesis of penicillin binding proteins.Journal of bacteriology · 2015Article
- Defining the region of Bacillus subtilis SpoIIIJ that is essential for its sporulation-specific function.Journal of bacteriology · 2014Article
- A conserved cysteine residue of Bacillus subtilis SpoIIIJ is important for endospore development.PloS one · 2014Article
- Comparative genomics of transport proteins in developmental bacteria: Myxococcus xanthus and Streptomyces coelicolor.BMC microbiology · 2013Article
- Interaction of Streptococcus mutans YidC1 and YidC2 with translating and nontranslating ribosomes.Journal of bacteriology · 2013Article
- Proteolysin, a novel highly thermostable and cosolvent-compatible protease from the thermophilic bacterium Coprothermobacter proteolyticus.Applied and environmental microbiology · 2013Article
- Roles of AtpI and two YidC-type proteins from alkaliphilic Bacillus pseudofirmus OF4 in ATP synthase assembly and nonfermentative growth.Journal of bacteriology · 2013Article
- Co-operation between different targeting pathways during integration of a membrane protein.The Journal of cell biology · 2012Article
- The genomic basis for the evolution of a novel form of cellular reproduction in the bacterium Epulopiscium.BMC genomics · 2012Article
- Regulation of ykrL (htpX) by Rok and YkrK, a novel type of regulator in Bacillus subtilis.Journal of bacteriology · 2012Article
- Recruitment of a species-specific translational arrest module to monitor different cellular processes.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Efficient overproduction of membrane proteins in Lactococcus lactis requires the cell envelope stress sensor/regulator couple CesSR.PloS one · 2011Article
- Expression and localization of SpoIISA toxin during the life cycle of Bacillus subtilis.Research in microbiology · 2010Article
- Divergent stalling sequences sense and control cellular physiology.Biochemical and biophysical research communications · 2010Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In all domains of life Oxa1p-like proteins are involved in membrane protein biogenesis. Bacillus subtilis, a model organism for gram-positive bacteria, contains two Oxa1p homologs: SpoIIIJ and YqjG. These molecules appear to be mutually exchangeable, although SpoIIIJ is specifically required for spore formation. SpoIIIJ and YqjG have been implicated in a posttranslocational stage of protein secretion. Here we show that the expression of either spoIIIJ or yqjG functionally compensates for the defects in membrane insertion due to YidC depletion in Escherichia coli. Both SpoIIIJ and YqjG complement the function of YidC in SecYEG-dependent and -independent membrane insertion of subunits of the cytochrome o oxidase and F(1)F(o) ATP synthase complexes. Furthermore, SpoIIIJ and YqjG facilitate membrane insertion of F(1)F(o) ATP synthase subunit c from both E. coli and B. subtilis into inner membrane vesicles of E. coli. When isolated from B. subtilis cells, SpoIIIJ and YqjG were found to be associated with the entire F(1)F(o) ATP synthase complex, suggesting that they have a role late in the membrane assembly process. These data demonstrate that the Bacillus Oxa1p homologs have a role in membrane protein biogenesis rather than in protein secretion.
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