ReviewAnnual review of genomics and human genetics2009
Genotype imputation.
Review in Annual review of genomics and human genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 710 papers, 16 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
710 citing papers in PubMed, 16 syntheses or guidelines pooled it.
- Chronic kidney disease in adults with sickle cell trait: a systematic review and meta-analysis.Blood advances · 2025Pooled it
- Disparities in ABO blood type determination across diverse ancestries: a systematic review and validation in the All of Us Research Program.Journal of the American Medical Informatics Association : JAMIA · 2024Pooled it
- Genome-wide association analyses identified novel susceptibility loci for pulmonary embolism among Han Chinese population.BMC medicine · 2023Pooled it
- Evidence of causality of low body mass index on risk of adolescent idiopathic scoliosis: a Mendelian randomization study.Frontiers in endocrinology · 2023Pooled it
- GWAS of Reproductive Traits in Large White Pigs on Chip and Imputed Whole-Genome Sequencing Data.International journal of molecular sciences · 2022Pooled it
- Population structure discovery in meta-analyzed microbial communities and inflammatory bowel disease using MMUPHin.Genome biology · 2022Pooled it
- False positive findings during genome-wide association studies with imputation: influence of allele frequency and imputation accuracy.Human molecular genetics · 2021Pooled it
- Revisiting the genome-wide significance threshold for common variant GWAS.G3 (Bethesda, Md.) · 2021Pooled it
- Shared genetic background between children and adults with attention deficit/hyperactivity disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020Pooled it
- Genetic control of CCL24, POR, and IL23R contributes to the pathogenesis of sarcoidosis.Communications biology · 2020Pooled it
- Multi-Ancestry Genome-Wide Association Study of Spontaneous Clearance of Hepatitis C Virus.Gastroenterology · 2019Pooled it
- Genome-wide association study of germline variants and breast cancer-specific mortality.British journal of cancer · 2019Pooled it
- Genome-wide meta-analysis and replication studies in multiple ethnicities identify novel adolescent idiopathic scoliosis susceptibility loci.Human molecular genetics · 2018Pooled it
- An international meta-analysis confirms the association of BNC2 with adolescent idiopathic scoliosis.Scientific reports · 2018Pooled it
- Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI.International journal of obesity (2005) · 2018Pooled it
- Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.Nature genetics · 2018Pooled it
- A population-specific genomic reference panel for Taiwan: NHRI-RP-1.Journal of biomedical science · 2026Article
- Multi-threshold polygenic risk improves hippocampal-based cognitive decline prediction.Genome medicine · 2026Article
- A Pseudohaploid-Based Imputation Strategy for Interspecific FMolecular ecology · 2026Article
- Selphi, a tool for improving genotype imputation accuracy.Scientific reports · 2026Article
650 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Genotype imputation is now an essential tool in the analysis of genome-wide association scans. This technique allows geneticists to accurately evaluate the evidence for association at genetic markers that are not directly genotyped. Genotype imputation is particularly useful for combining results across studies that rely on different genotyping platforms but also increases the power of individual scans. Here, we review the history and theoretical underpinnings of the technique. To illustrate performance of the approach, we summarize results from several gene mapping studies. Finally, we preview the role of genotype imputation in an era when whole genome resequencing is becoming increasingly common.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.