ArticleJournal of the American Chemical Society2009
Intelligent medical diagnostics via molecular logic.
Article in Journal of the American Chemical Society, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 152 citations in OpenAlex.
- White light emitting molecular logic gates.Smart molecules : open access · 2026Review
- Programmable AND-gate strategy to reduce false positives in rolling circle amplification.Biosensors & bioelectronics · 2026Article
- Fluorescence-Based Multimodal DNA Logic Gates.Nanomaterials (Basel, Switzerland) · 2024Article
- Lab-on-a-molecule and multi-analyte sensing.Frontiers in chemistry · 2024Review
- Metallocene-Naphthalimide Derivatives: The Effect of Geometry, DFT Methodology, and Transition Metals on Absorption Spectra.Molecules (Basel, Switzerland) · 2023Article
- Fluorescent Probes as a Tool in Diagnostic and Drug Delivery Systems.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Solvent-polarity reconfigurable fluorescent 4-piperazino-RSC advances · 2022Article
- Implementation of Arithmetic and Nonarithmetic Functions on a Label-free and DNA-based Platform.Scientific reports · 2016Article
- Picking Out Logic Operations in a Naphthalene β-Diketone Derivative by Using Molecular Encapsulation, Controlled Protonation, and DNA Binding.ChemistryOpen · 2015Article
- A universal platform for building molecular logic circuits based on a reconfigurable three-dimensional DNA nanostructure.Chemical science · 2015Article
- Bridging the Two Worlds: A Universal Interface between Enzymatic and DNA Computing Systems.Angewandte Chemie (International ed. in English) · 2015Article
- Implementation of Arithmetic Functions on a Simple and Universal Molecular Beacon Platform.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2015Article
- Review
- A highly parallel microfluidic droplet method enabling single-molecule counting for digital enzyme detection.Biomicrofluidics · 2014Article
- An all-photonic molecule-based parity generator/checker for error detection in data transmission.Journal of the American Chemical Society · 2013Article
- Article
- Measuring binding of protein to gel-bound ligands using magnetic levitation.Journal of the American Chemical Society · 2012Article
- Particles and microfluidics merged: perspectives of highly sensitive diagnostic detection.Mikrochimica acta · 2012Article
- An all-photonic molecule-based D flip-flop.Journal of the American Chemical Society · 2011Article
- OFF-ON-OFF fluorescence switch with T-latch function.Organic letters · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
In this communication, we describe the integration of microarray sensor technology with logic capability for screening combinations of proteins and DNA in a biological sample. In this system, we have demonstrated the use of a single platform amenable to both protein detection and protein-DNA detection using molecular logic gates. The pattern of protein and DNA inputs results in fluorescence outputs according to a truth table for AND and INHIBIT gates, thereby demonstrating the feasibility of performing medical diagnostics using a logic gate design. One possible application of this technique would be direct screening of various medical conditions that are dependent on combinations of diagnostic markers.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.