ArticleGenome biology2009
Assisted assembly: how to improve a de novo genome assembly by using related species.
Article in Genome biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
30 citing papers in PubMed.
- Finishing a complete giraffe genome from telomere to telomere with Verkko-Fillet.Cell genomics · 2026Article
- Finishing a complete giraffe genome from telomere to telomere with Verkko-Fillet.bioRxiv : the preprint server for biology · 2025Article
- Comparative Genomics Supports That Brazilian BioethanolFrontiers in microbiology · 2021Article
- Nucleotide diversity of functionally different groups of immune response genes in Old World camels based on newly annotated and reference-guided assemblies.BMC genomics · 2020Article
- A linked-read approach to museomics: Higher quality de novo genome assemblies from degraded tissues.Molecular ecology resources · 2020Article
- Evolutionary superscaffolding and chromosome anchoring to improve Anopheles genome assemblies.BMC biology · 2020Article
- Classification of Grain Amaranths Using Chromosome-Level Genome Assembly of Ramdana,Frontiers in plant science · 2020Article
- A Near-Chromosome Level Genome Assembly ofFrontiers in genetics · 2020Article
- Chromosome-level genome assembly for giant panda provides novel insights into Carnivora chromosome evolution.Genome biology · 2019Article
- Chromosome assembly of large and complex genomes using multiple references.Genome research · 2018Article
- Reliable Detection of Herpes Simplex Virus Sequence Variation by High-Throughput Resequencing.Viruses · 2017Article
- The A, C, G, and T of Genome Assembly.BioMed research international · 2016Review
- Misassembly detection using paired-end sequence reads and optical mapping data.Bioinformatics (Oxford, England) · 2015Article
- Harnessing cross-species alignment to discover SNPs and generate a draft genome sequence of a bighorn sheep (Ovis canadensis).BMC genomics · 2015Article
- RECORD: Reference-Assisted Genome Assembly for Closely Related Genomes.International journal of genomics · 2015Article
- Successful Recovery of Nuclear Protein-Coding Genes from Small Insects in Museums Using Illumina Sequencing.PloS one · 2015Article
- A field guide to whole-genome sequencing, assembly and annotation.Evolutionary applications · 2014Review
- AlignGraph: algorithm for secondary de novo genome assembly guided by closely related references.Bioinformatics (Oxford, England) · 2014Article
- Whole genome sequencing of the black grouse (Tetrao tetrix): reference guided assembly suggests faster-Z and MHC evolution.BMC genomics · 2014Article
- HyDA-Vista: towards optimal guided selection of k-mer size for sequence assembly.BMC genomics · 2014Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We describe a new assembly algorithm, where a genome assembly with low sequence coverage, either throughout the genome or locally, due to cloning bias, is considerably improved through an assisting process via a related genome. We show that the information provided by aligning the whole-genome shotgun reads of the target against a reference genome can be used to substantially improve the quality of the resulting assembly.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.