Trial reportClinical cardiology2009
Systolic blood pressure and subjective well-being in patients with coronary artery disease.
Trial report in Clinical cardiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00133692 (INternational VErapamil SR Trandolapril STudy), which is not on this map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
INternational VErapamil SR Trandolapril STudy
Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Associations between daily home blood pressure measurements and self-reports of lifestyle and symptoms in primary care: the PERHIT study.Scandinavian journal of primary health care · 2024Trial
- Trial
- Trial
- Mortality implications of angina and blood pressure in hypertensive patients with coronary artery disease: New data from extended follow-up of the International Verapamil/Trandolapril Study (INVEST).Clinical cardiology · 2013Trial
- Ethnic-Specific Threshold Analysis and BMI and Waist Circumference Cutoffs for Cardiovascular Disease and Subjective Wellbeing: Results using Data from the UK Biobank.Journal of racial and ethnic health disparities · 2025Article
- Life satisfaction as compared with traditional risk factors in relation to incident cardiovascular diseases.European journal of epidemiology · 2025Article
- The role of perceived social support in subjective wellbeing among working-age U.S. adults with and without limitations in activities of daily living.Disability and health journal · 2025Article
- Measuring subjective wellbeing in patients with heart disease: relationship and comparison between health-related quality of life instruments.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Article
- Health-related quality of life in persons with apparent treatment-resistant hypertension on at least four antihypertensives.Journal of human hypertension · 2016Article
- Quality of Life in Treatment-Resistant Hypertension.Current hypertension reports · 2015Review
- Exercise performance, physical activity, and health-related quality of life in participants with stable angina.Angiology · 2011Article
- INVEST revisited: review of findings from the International Verapamil SR-Trandolapril Study.Expert review of cardiovascular therapy · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundLimited information exists regarding the association between subjective well-being (SWB) and systolic blood pressure (SBP) among hypertensive patients with coronary artery disease (CAD). HYPOTHESIS: We tested the hypothesis that there is an association between SBP and SWB.
methodsWe studied 22,576 hypertensive CAD patients > or = 50 years old in the INternational VErapamil SR-Trandolapril Study (INVEST), a randomized, blinded-endpoint trial of antihypertensive therapy in stable CAD patients. At each study visit, patients rated their SWB in the previous 4 weeks as "excellent," "good," "fair," or "poor" prior to SBP recordings. The outcome measure was SWB of "fair" or "poor." A longitudinal analysis using generalized estimating equations was performed to assess the association between SBP and odds of reporting fair/poor SWB, controlling for baseline SWB of fair/poor and angina reported during the study.
resultsPatients with higher SBP had higher odds of reporting fair/poor SWB. Specifically, compared with patients with SBP of < or = 120, patients with SBP 140-150 > 150 - < or = 160 and > 160 had about 90% and 2.5 times greater odds of feeling fair/poor, respectively (adjusted odds ratio [OR]: 1.5990, 95% confidence interval [CI]: 1.81-2.00 and adjusted OR: 2.53, 95% CI: 2.41-2.66). Those who reported angina in the 4 wks prior to a protocol visit had 2.2 times greater odds of reporting fair/poor SWB (adjusted OR: 2.2, 95% CI: 2.13-2.27). Female gender, black race, history of smoking, diabetes, myocardial infarction, stroke, and cancer also increased the odds of reporting fair/poor SWB.
conclusionsAmong hypertensive CAD patients, higher on-treatment SBP is associated with greater odds of fair/poor SWB during follow-up.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.