ArticleDevelopment (Cambridge, England)2009
Regulation of preprocambial cell state acquisition by auxin signaling in Arabidopsis leaves.
Article in Development (Cambridge, England), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers.
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Who cites it
120 citing papers in PubMed, 282 citations in OpenAlex.
- Genome-Wide Characterization of thePlants (Basel, Switzerland) · 2026Article
- ARF6 integrates auxin and gibberellin signaling to promote stone cell lignification in pear via the HB49-MYB169 module.The New phytologist · 2026Article
- The role of FRUITFULL controlling cell cycle during early flower development revealed by time-series snRNA-seq experiments.Genome biology · 2025Article
- RNA processing/modifying enzymes play key roles in the response to thermospermine in Arabidopsis thaliana.The Plant journal : for cell and molecular biology · 2025Article
- Decay drives RNA abundance regulation using three distinct regulatory mechanisms.bioRxiv : the preprint server for biology · 2025Article
- The role of auxin transport through plasmodesmata in leaf vein canalization and patterning.Frontiers in plant science · 2025Article
- A major role of class III HD-ZIPs in promoting sugar beet cyst nematode parasitism in Arabidopsis.PLoS pathogens · 2024Article
- Review
- The Ins and Outs of Homeodomain-Leucine Zipper/Hormone Networks in the Regulation of Plant Development.International journal of molecular sciences · 2024Review
- To bind or not to bind: how AUXIN RESPONSE FACTORs select their target genes.Journal of experimental botany · 2023Review
- Game of thrones among AUXIN RESPONSE FACTORs-over 30 years of MONOPTEROS research.Journal of experimental botany · 2023Review
- Article
- HD-ZIP III-dependent local promotion of brassinosteroid synthesis suppresses vascular cell division in Arabidopsis root apical meristem.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Gibberellins promote polar auxin transport to regulate stem cell fate decisions in cambium.Nature plants · 2023Article
- An Integration of Linkage Mapping and GWAS Reveals the Key Genes for Ear Shank Length in Maize.International journal of molecular sciences · 2022Article
- Leaf vein patterning is regulated by the aperture of plasmodesmata intercellular channels.PLoS biology · 2022Article
- Article
- AUXIN RESPONSE FACTOR7 integrates gibberellin and auxin signaling via interactions between DELLA and AUX/IAA proteins to regulate cambial activity in poplar.The Plant cell · 2022Article
- Article
- CkREV Enhances the Drought Resistance ofInternational journal of molecular sciences · 2022Article
60 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The principles underlying the formation of veins in the leaf have long intrigued developmental biologists. In Arabidopsis leaves, files of anatomically inconspicuous subepidermal cells that will elongate into vein-forming procambial cells selectively activate ATHB8 gene expression. The biological role of ATHB8 in vein formation and the molecular events that culminate in acquisition of the ATHB8 preprocambial cell state are unknown, but intertwined pathways of auxin transport and signal transduction have been implicated in defining paths of vascular strand differentiation. Here we show that ATHB8 is required to stabilize preprocambial cell specification against auxin transport perturbations, to restrict preprocambial cell state acquisition to narrow fields and to coordinate procambium formation within and between veins. We further show that ATHB8 expression at preprocambial stages is directly and positively controlled by the auxin-response transcription factor MONOPTEROS (MP) through an auxin-response element in the ATHB8 promoter. We finally show that the consequences of loss of ATHB8 function for vein formation are masked by MP activity. Our observations define, at the molecular level, patterning inputs of auxin signaling in vein formation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.