ArticleCancer2009
Prognosis and patterns of care in elderly patients with glioma.
Article in Cancer, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Prognostic value of surgical resection over biopsy in elderly patients with glioblastoma: a meta-analysis.Journal of neuro-oncology · 2024Pooled it
- Supratentorial glioblastoma multiforme: the role of surgical resection versus biopsy among older patients.Annals of surgical oncology · 2011Trial
- Glioblastoma in the oldest old: Clinical characteristics, therapy, and outcome in patients aged 80 years and older.Neuro-oncology practice · 2024Article
- Surgeon experience in glioblastoma surgery of the elderly-a multicenter, retrospective cohort study.Journal of neuro-oncology · 2023Article
- Do elderly patients (≥ 75 years old) with glioblastoma benefit from more radical surgeries in the era of temozolomide?Neurosurgical review · 2022Article
- A Population-Based Study of Treatment and Survival in Older Glioma Patients.JNCI cancer spectrum · 2022Article
- The Risk of Heart Disease-Related Death Among Anaplastic Astrocytoma Patients After Chemotherapy: A SEER Population-Based Analysis.Frontiers in oncology · 2022Article
- Surgical strategies for older patients with glioblastoma.Journal of neuro-oncology · 2021Article
- Age is associated with unfavorable neuropathological and radiological features and poor outcome in patients with WHO grade 2 and 3 gliomas.Scientific reports · 2021Article
- Clinical characteristics and risk factors of perioperative outcomes in elderly patients with intracranial tumors.Neurosurgical review · 2021Article
- Molecular features and clinical outcomes in surgically treated low-grade diffuse gliomas in patients over the age of 60.Journal of neuro-oncology · 2019Article
- Genomic and Molecular Characterization of Brain Tumors in Asian and Non-Asian Patients of Los Angeles: A Single Institution Analysis.Brain tumor research and treatment · 2017Article
- Management of glioblastoma in elderly patients.Journal of the neurological sciences · 2017Review
- Butterfly Tumor of the Corpus Callosum: Clinical Characteristics, Diagnosis, and Survival Analysis.Journal of neurosciences in rural practice · 2017Article
- Article
- Management of elderly patients with gliomas.The oncologist · 2014Review
- Treating glioblastoma patients with poor performance status: where do we go from here?CNS oncology · 2014Review
- High-grade glioma in elderly patients: can the oncogeriatrician help?Clinical interventions in aging · 2013Review
- Presentation, management, and outcome of elderly patients with newly-diagnosed anaplastic astrocytoma.Journal of neuro-oncology · 2012Article
- A novel volume-age-KPS (VAK) glioblastoma classification identifies a prognostic cognate microRNA-gene signature.PloS one · 2012Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe current study was conducted to evaluate the patterns of care and survival of older adults with oligodendroglioma (OLI) and astrocytoma (AST) from a large population-based registry.
methodsThe authors identified a cohort of OLI and AST patients aged >or=65 years from Surveillance, Epidemiology and End Results (SEER) cancer registry data linked with Medicare claims between 1994 and 2002. Patients with a diagnosis of glioblastoma were excluded. The impact of demographic characteristics and comorbidities on the probability of undergoing surgical resection, radiotherapy (RT), and chemotherapy within 6 months of diagnosis was assessed using multivariate logistic regression.
resultsA total of 1067 patients (891 with AST and 176 with OLI) were included; the median survival was 9 months for patients with low-grade AST, 4 months for patients with anaplastic AST, 57 months for patients with low-grade OLI, and 9 months for patients with anaplastic OLI. Approximately 54% of patients underwent resection at the time of diagnosis; 66% received RT, and 13% received chemotherapy within 6 months of diagnosis. In a multivariate regression analysis, age and tumor grade were found to be the most significant predictors of resection, RT, or chemotherapy. Patients with anaplastic tumors were treated with resection, RT, and chemotherapy more often than patients with low-grade tumors, and OLI patients received chemotherapy more frequently than AST.
conclusionsData from the current study suggested that histologic diagnosis and tumor grade retained significant prognostic value in this elderly AST and OLI population. Furthermore, age and tumor grade were found to influence the probability of undergoing surgery, RT, and chemotherapy in this cohort.
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