ArticlePLoS neglected tropical diseases2009
Neglected tropical diseases in sub-saharan Africa: review of their prevalence, distribution, and disease burden.
Article in PLoS neglected tropical diseases, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07506967 (Early Detection and Management of SKIN-related negleCted Tropical Diseases Using Artificial Intelligence in Sub-saharan afRica), which is not on this map. Cited by 633 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Early Detection and Management of SKIN-related negleCted Tropical Diseases Using Artificial Intelligence in Sub-saharan afRica (SkincAIr)
Who cites it
633 citing papers in PubMed, 8 syntheses or guidelines pooled it, 1,296 citations in OpenAlex.
- The health and economic burden of podoconiosis in East Africa: A systematic review and meta-analysis of health outcomes with narrative synthesis of economic evidence.PLoS neglected tropical diseases · 2026Pooled it
- Prevalence and associated risk factors of human leishmaniasis in sub-Saharan Africa: an umbrella review.BMC infectious diseases · 2025Pooled it
- Hookworm infection and its determinants among schoolchildren in Ethiopia: a systematic review and meta-analysis.BMC infectious diseases · 2024Pooled it
- Prevalence of human visceral leishmaniasis and its risk factors in Eastern Africa: a systematic review and meta-analysis.Frontiers in public health · 2024Pooled it
- Effects of paediatric schistosomiasis control programmes in sub-Saharan Africa: A systematic review.PloS one · 2024Pooled it
- Prevalence of soil-transmitted helminths infections among preschool and school-age children in Ethiopia: a systematic review and meta-analysis.Global health research and policy · 2022Pooled it
- Burden of intestinal parasitic infections among pregnant women in Ethiopia: a systematic review and meta-analysis.Infection · 2021Pooled it
- A systematic review and meta-analysis on prevalence and distribution of Taenia and Echinococcus infections in Ethiopia.Parasites & vectors · 2021Pooled it
- Impact of Anthelmintic Therapy for Invasive Helminth Infection on Microbial Translocation, Inflammation, and Immune Response among Ugandans Living with HIV: A Randomized Proof of Concept Study.The American journal of tropical medicine and hygiene · 2025Trial
- Toward transgenic multicellular parasites: CRISPR-Cas12a germline editing ofScience advances · 2026Article
- How Imported Pathology Becomes Overlooked as Resources Increase: An Example of a Neglected Tropical Disease (NTD).Tropical medicine and infectious disease · 2026Article
- Distribution of Mother-to-Child Transmitted (MTCT) Infections and Socioeconomic Vulnerability Within the Gran Chaco Region.Tropical medicine and infectious disease · 2026Article
- Praziquantel efficacy and post-treatment reinfection and incidence of Schistosoma mansoni among school-aged children in Northern Uganda: a 24-week cohort study in a high transmission focus.BMC infectious diseases · 2026Article
- Post-market surveillance of albendazole tablet brands in Kenya: Implications for deworming programs and clinical outcomes.PLoS neglected tropical diseases · 2026Article
- Assessment of community knowledge, attitudes, and practices related to schistosomiasis in a hyper-endemic region of the Democratic Republic of Congo: mixed methods.BMC public health · 2026Article
- Profiling Disease Patterns Using ICD-11 at a University Hospital in Ghana: A Retrospective Analysis of Cross-Sectional Data From 2018 to 2021.Health science reports · 2026Article
- The Potential of Bioinformatics in Revolutionizing Disease Diagnosis in Sub-Saharan Africa: A Narrative Review.Health science reports · 2026Article
- Sub-microscopic schistosomiasis and soil-transmitted helminths in school children: molecular diagnostic evidence and implications for disease elimination.Scientific reports · 2026Article
- Abundance and Seasonal Variations of Snail Intermediate Hosts of Schistosomiasis in the Federal Capital Territory, Abuja, Nigeria.International journal of environmental research and public health · 2026Article
- Prevalence, infection intensity, and risk factors of soil-transmitted helminthiasis and intestinal schistosomiasis among schoolchildren in Southern Ethiopia.PLoS neglected tropical diseases · 2026Article
573 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The neglected tropical diseases (NTDs) are the most common conditions affecting the poorest 500 million people living in sub-Saharan Africa (SSA), and together produce a burden of disease that may be equivalent to up to one-half of SSA's malaria disease burden and more than double that caused by tuberculosis. Approximately 85% of the NTD disease burden results from helminth infections. Hookworm infection occurs in almost half of SSA's poorest people, including 40-50 million school-aged children and 7 million pregnant women in whom it is a leading cause of anemia. Schistosomiasis is the second most prevalent NTD after hookworm (192 million cases), accounting for 93% of the world's number of cases and possibly associated with increased horizontal transmission of HIV/AIDS. Lymphatic filariasis (46-51 million cases) and onchocerciasis (37 million cases) are also widespread in SSA, each disease representing a significant cause of disability and reduction in the region's agricultural productivity. There is a dearth of information on Africa's non-helminth NTDs. The protozoan infections, human African trypanosomiasis and visceral leishmaniasis, affect almost 100,000 people, primarily in areas of conflict in SSA where they cause high mortality, and where trachoma is the most prevalent bacterial NTD (30 million cases). However, there are little or no data on some very important protozoan infections, e.g., amebiasis and toxoplasmosis; bacterial infections, e.g., typhoid fever and non-typhoidal salmonellosis, the tick-borne bacterial zoonoses, and non-tuberculosis mycobaterial infections; and arboviral infections. Thus, the overall burden of Africa's NTDs may be severely underestimated. A full assessment is an important step for disease control priorities, particularly in Nigeria and the Democratic Republic of Congo, where the greatest number of NTDs may occur.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.