Evidence map›Paper›PMID 19707535›Full record

ArticleHPB surgery : a world journal of hepatic, pancreatic and biliary surgery2009

Interleukin-8 producing hepatocellular carcinoma with pyrexia.

Norifumi Harimoto, Ken Shirabe, Tomoyuki Abe, Kiyoshi Kajiyama, Takashi Nagaie, Tomonobu Gion, Yousuke Kuroda, Yoshihiko Maehara

Open access · hybridAbstract readCase Reports
In one paragraph

Article in HPB surgery : a world journal of hepatic, pancreatic and biliary surgery, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Norifumi HarimotoDepartment of Surgery, Iizuka Hospital, Fukuoka 820-8505, Japan. nharimotoh1@aih-net.com
Ken Shirabe
Tomoyuki Abe
Kiyoshi Kajiyama
Takashi Nagaie
Tomonobu Gion
Yousuke Kuroda
Yoshihiko Maehara
Aso Iizuka Hospital · JPKyushu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We discuss a patient who had poorly differentiated HCC with pyrexia and high CRP in laboratory data, which are not commonly observed in the usual HCC. A 50-year-old man with a history of liver dysfunction was admitted with a chief complaint of a prolonged fever and general fatigue. Preoperative diagnosis was HCC with portal vein tumor thrombus. Posterior segmentectomy of the liver and thrombectomy was performed. Rapid tumor recurrence occurred after surgery, and he died 79 days after the operation. Immunohistochemical stain of HCC in this patient revealed the production of proinflammatory cytokine, interleukin-8 (IL-8). IL-8 production may have contributed to the high fever, high inflammatory reaction, and poor prognosis in this case.

Indexed as

Carcinoma, HepatocellularC-Reactive ProteinFatal OutcomeFeverHumansImmunohistochemistryInterleukin-8Liver NeoplasmsMaleMiddle AgedNeoplasm InvasivenessTomography, X-Ray ComputedC-Reactive ProteinInterleukin-8

Identifiers

PMID19707535
PMCPMC2730579
OpenAlexW2066936618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.