Evidence map›Paper›PMID 19707109›Full record

ArticleSexually transmitted diseases2009

Association of age at first sex with HIV-1, HSV-2, and other sexual transmitted infections among women in northern Tanzania.

Musie Ghebremichael, Ulla Larsen, Elijah Paintsil

Abstract read
In one paragraph

Article in Sexually transmitted diseases, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Musie GhebremichaelDepartment of Biostatistics, Harvard University School of Public Health and Dana Farber Cancer Institute, 3 Blackfan Circle, Boston, MA 02115, USA. musie@jimmy.harvard.edu
Ulla Larsen
Elijah Paintsil

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI Daniel Lingwood · 2004 to 2026
$94.4M
A Community Study of Infertility in Northern TanzaniaR01HD041202 · NICHD · UNIVERSITY OF MARYLAND COLLEGE PK CAMPUS · PI LARSEN, ULLA M · 2001 to 2004
$1.2M
HIV Nucleoside Analogs Translational Studies: Resistance and MetabolismK08AI074404 · NIAID · YALE UNIVERSITY · PI PAINTSIL, ELIJAH · 2008 to 2012
$629k
NIAID NIH HHS K08 AI074404NIAID NIH HHS P30 AI060354NIAID NIH HHS P30-AI 060354NICHD NIH HHS R01 HD041202NICHD NIH HHS R01 HD41202
6 · The paper itself

Abstract

backgroundTo examine the association between age at first sex and the prevalence of sexually transmitted infections (STIs), including HIV-1 and HSV-2, in women in Moshi urban district, northern Tanzania.

methodsA total of 2019 women aged 20 to 44 were randomly selected in a 2-stage sampling from Moshi urban district, northern Tanzania. Information on demographics and sexual behaviors were obtained. Blood and urine samples were drawn for testing of HIV-1, HSV-2, and other STIs.

resultsWomen who had their first sexual intercourse at age between 18 and 19 (OR = 0.66; 95% CI = 0.50-0.86) or 20+ (OR = 0.46; 95% CI = 0.36-0.60) were less likely to have STIs, including HIV-1 and HSV-2, than women who had their first intercourse before their 18th birthday. The hazards of having had first sex at an earlier age were significantly higher for women who tested positive for STIs (HR = 1.52; 95% CI: 1.37-1.69) or had STI symptoms (HR = 1.17; 95% CI: 1.05-1.30). Early age at first sex was associated with having a regular noncohabiting partner (HR = 1.40; 95% CI: 1.23-1.58), female circumcision (HR = 1.20; 95% CI: 1.02-1.40), and coercion at first intercourse (HR = 1.47; 95% CI: 1.15-1.89).

conclusionsIn sub-Saharan Africa, where the prevalence of HIV and other STIs is high, a better understanding of the determinants of the age at first sex is crucial for HIV/STI prevention programs. Prevention programs should not only aim at delaying the age at first sex but also address factors leading to early age at first sex.

Indexed as

CoitusAdultAge FactorsFemaleHerpes GenitalisHerpesvirus 2, HumanHIV-1HIV InfectionsHumansInterviews as TopicPrevalenceSexually Transmitted DiseasesTanzaniaYoung Adult

Identifiers

PMID19707109
PMCPMC3529537

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.