ArticleThe Plant cell2009
Arabidopsis cortical microtubules are initiated along, as well as branching from, existing microtubules.
Article in The Plant cell, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
59 citing papers in PubMed, 129 citations in OpenAlex.
- Towards a systems-level view of the microtubule cytoskeleton and its functions in physiology and disease.Nature reviews. Molecular cell biology · 2026Review
- Arabidopsis AUGMIN8 Contains Two Independent Microtubule Association Domains.Cytoskeleton (Hoboken, N.J.) · 2026Article
- Transverse cortical microtubule arrays form persistent unipolar domains in hypocotyl cells ofMolecular biology of the cell · 2025Article
- Branching, crosslinking, and decentralization of microtubules accelerates intracellular assembly.Biophysical journal · 2025Article
- Conflicting roles of cell geometry, microtubule deflection, and orientation-dependent dynamic instability in cortical array organization.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Microtubule-based nucleation results in a large sensitivity to cell geometry of the plant cortical array.PLoS computational biology · 2025Article
- Microtubule flexibility, microtubule-based nucleation and ROP pattern co-alignment enhance protoxylem microtubule patterning.Quantitative plant biology · 2025Article
- Integrated model of the vertebrate augmin complex.Nature communications · 2023Article
- Microtubule nucleation complex behavior is critical for cortical array homogeneityProceedings of the National Academy of Sciences of the United States of America · 2022Article
- How Microtubules Build the Spindle Branch by Branch.Annual review of cell and developmental biology · 2022Review
- Imaging the living plant cell: From probes to quantification.The Plant cell · 2022Review
- Finding a right place to cut: How katanin is targeted to cellular severing sites.Quantitative plant biology · 2022Review
- An anchoring complex recruits katanin for microtubule severing at the plant cortical nucleation sites.Nature communications · 2021Article
- Long-term single-cell imaging and simulations of microtubules reveal principles behind wall patterning during proto-xylem development.Nature communications · 2021Article
- A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation.Quantitative plant biology · 2021Article
- Direct observation of branching MT nucleation in living animal cells.The Journal of cell biology · 2019Article
- Live-cell imaging of the cytoskeleton in elongating cotton fibres.Nature plants · 2019Article
- CLASP Facilitates Transitions between Cortical Microtubule Array Patterns.Plant physiology · 2018Article
- The Microtubule-Associated Protein IQ67 DOMAIN5 Modulates Microtubule Dynamics and Pavement Cell Shape.Plant physiology · 2018Article
- The Arabidopsis SPIRAL2 Protein Targets and Stabilizes Microtubule Minus Ends.Current biology : CB · 2018Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The principles by which cortical microtubules self-organize into a global template hold important implications for cell wall patterning. Microtubules move along bundles of microtubules, and neighboring bundles tend to form mobile domains that flow in a common direction. The bundles themselves move slowly and for longer than the individual microtubules, with domains describing slow rotary patterns. Despite this tendency for colinearity, microtubules have been seen to branch off extant microtubules at approximately 45 degrees . To examine this paradoxical behavior, we investigated whether some microtubules may be born on and grow along extant microtubule(s). The plus-end markers Arabidopsis thaliana end binding protein 1a, AtEB1a-GFP, and Arabidopsis SPIRAL1, SPR1-GFP, allowed microtubules of known polarity to be distinguished from underlying microtubules. This showed that the majority of microtubules do branch but in a direction heavily biased toward the plus end of the mother microtubule: few grow backward, consistent with the common polarity of domains. However, we also found that a significant proportion of emergent comets do follow the axes of extant microtubules, both at sites of apparent microtubule nucleation and at cross-over points. These phenomena help explain the persistence of bundles and counterbalance the tendency to branch.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.