ReviewHuman genomics2009
Comparative transcriptome analyses of Pseudomonas aeruginosa.
Review in Human genomics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Acyloxyacyl hydrolase promotes pulmonary defense by preventing alveolar macrophage tolerance.PLoS pathogens · 2023Article
- Oxidative Stress Response inPathogens (Basel, Switzerland) · 2021Review
- Pseudomonas aeruginosa core metabolism exerts a widespread growth-independent control on virulence.Scientific reports · 2020Article
- Determining the Different Mechanisms Used byFrontiers in microbiology · 2020Article
- Transcriptomic Response inInternational journal of microbiology · 2020Article
- A Small RNA Transforms the Multidrug Resistance of Pseudomonas aeruginosa to Drug Susceptibility.Molecular therapy. Nucleic acids · 2019Article
- Biofilm formation and transcriptome analysis of Streptococcus gallolyticus subsp. gallolyticus in response to lysozyme.PloS one · 2018Article
- Substrate Binding Protein DppA1 of ABC Transporter DppBCDF Increases Biofilm Formation inFrontiers in microbiology · 2018Article
- Capture compound mass spectrometry--a powerful tool to identify novel c-di-GMP effector proteins.Journal of visualized experiments : JoVE · 2015Article
- Article
- Deep sequencing analyses expands the Pseudomonas aeruginosa AmpR regulon to include small RNA-mediated regulation of iron acquisition, heat shock and oxidative stress response.Nucleic acids research · 2014Article
- Pseudomonas aeruginosa uses multiple pathways to acquire iron during chronic infection in cystic fibrosis lungs.Infection and immunity · 2013Article
- Effect of long-term starvation in salty microcosm on biofilm formation and motility in Pseudomonas aeruginosa.World journal of microbiology & biotechnology · 2013Article
- A dynamic and intricate regulatory network determines Pseudomonas aeruginosa virulence.Nucleic acids research · 2013Review
- Microbial adhesion and biofilm formation on microfiltration membranes: a detailed characterization using model organisms with increasing complexity.BioMed research international · 2013Article
- The regulatory repertoire of Pseudomonas aeruginosa AmpC ß-lactamase regulator AmpR includes virulence genes.PloS one · 2012Article
- Genome-wide identification of Pseudomonas aeruginosa virulence-related genes using a Caenorhabditis elegans infection model.PLoS pathogens · 2012Article
- Metabolism and function of phenazines in bacteria: impacts on the behavior of bacteria in the environment and biotechnological processes.Applied microbiology and biotechnology · 2010Review
- Why is Pseudomonas aeruginosa a pathogen?F1000 biology reports · 2010Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
One of the hallmarks of bacterial survival is their ability to adapt rapidly to changing environmental conditions. Niche adaptation is a response to the signals received that are relayed, often to regulators that modulate gene expression. In the post-genomic era, DNA microarrays are used to study the dynamics of gene expression on a global scale. Numerous studies have used Pseudomonas aeruginosa--a Gram-negative environmental and opportunistic human pathogenic bacterium--as the model organism in whole-genome transcriptome analysis. This paper reviews the transcriptome studies that have led to immense advances in our understanding of the biology of this intractable human pathogen. Comparative analysis of 23 P. aeruginosa transcriptome studies has led to the identification of a unique set of genes that are signal specific and a core set that is differentially regulated. The 303 genes in the core set are involved in bacterial homeostasis, making them attractive therapeutic targets.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.