ArticleNeurobiology of learning and memory2010
Medial auditory thalamic input to the lateral pontine nuclei is necessary for auditory eyeblink conditioning.
Article in Neurobiology of learning and memory, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 43 citations in OpenAlex.
- Central amygdala contributes to stimulus facilitation and pre-stimulus vigilance during cerebellar learning.Neurobiology of learning and memory · 2024Article
- Role of cerebellar cortex in associative learning and memory in guinea pigs.Open life sciences · 2022Article
- Medial Auditory Thalamus Is Necessary for Expression of Auditory Trace Eyelid Conditioning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Cerebellar Processing Common to Delay and Trace Eyelid Conditioning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Amygdala central nucleus modulation of cerebellar learning with a visual conditioned stimulus.Neurobiology of learning and memory · 2018Article
- Article
- Amygdala Modulation of Cerebellar Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Cerebellar learning mechanisms.Brain research · 2015Review
- The impact of hippocampal lesions on trace-eyeblink conditioning and forebrain-cerebellar interactions.Behavioral neuroscience · 2015Review
- Optogenetic stimulation of mPFC pyramidal neurons as a conditioned stimulus supports associative learning in rats.Scientific reports · 2015Article
- Medial auditory thalamus is necessary for acquisition and retention of eyeblink conditioning to cochlear nucleus stimulation.Learning & memory (Cold Spring Harbor, N.Y.) · 2015Article
- Eyeblink Conditioning and Novel Object Recognition in the Rabbit: Behavioral Paradigms for Assaying Psychiatric Diseases.Frontiers in psychiatry · 2015Review
- Learning-related neuronal activity in the ventral lateral geniculate nucleus during associative cerebellar learning.Journal of neurophysiology · 2014Article
- Sensory system development influences the ontogeny of eyeblink conditioning.Developmental psychobiology · 2014Article
- Awareness is essential for differential delay eyeblink conditioning with soft-tone but not loud-tone conditioned stimuli.Neuroscience bulletin · 2014Article
- Axonal sprouting and formation of terminals in the adult cerebellum during associative motor learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Inactivation of the ventral lateral geniculate and nucleus of the optic tract impairs retention of visual eyeblink conditioning.Behavioral neuroscience · 2013Article
- Visual cortical contributions to associative cerebellar learning.Neurobiology of learning and memory · 2013Article
- Blocking glutamate-mediated inferior olivary signals abolishes expression of conditioned eyeblinks but does not prevent their acquisition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Auditory and visual conditioned stimulus (CS) pathways for eyeblink conditioning were investigated with reversible inactivation of the medial (MPN) or lateral (LPN) pontine nuclei. In Experiment 1, Long-Evans rats were given three phases of eyeblink conditioning. Phase 1 consisted of three training sessions with electrical stimulation of the medial auditory thalamic nuclei (MATN) paired with a periorbital shock unconditioned stimulus (US). An additional session was given with a muscimol (0.5muL, 10mM) or saline infusion targeting the LPN followed by a recovery session with no infusions. The same training and testing sequence was then repeated with either a tone or light CS in phases 2 and 3 (counterbalanced). Experiment 2 consisted of the same training as Experiment 1 except that muscimol or saline was infused in the MPN during the retention tests. Muscimol infusions targeting the LPN severely impaired retention of eyeblink conditioned responses (CRs) to the MATN stimulation and tone CSs but only partially reduced CR percentage to the light CS. Muscimol infusions that targeted the MPN had a larger effect on CR retention to the light CS relative to MATN stimulation or tone CSs. The results provide evidence that the auditory CS pathway necessary for delay eyeblink conditioning includes the MATN-LPN projection and the visual CS pathway includes the MPN.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.