ArticleWorld journal of gastroenterology2009
Current clinical approach to achalasia.
Article in World journal of gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
57 citing papers in PubMed, 3 syntheses or guidelines pooled it, 143 citations in OpenAlex.
- Robotic versus laparoscopic heller myotomy for esophageal achalasia: an updated systematic review and meta-analysis.Langenbeck's archives of surgery · 2025Pooled it
- Surgical approaches for achalasia and obesity: a systematic review and patient-level meta-analysis.Langenbeck's archives of surgery · 2023Pooled it
- SAGES guidelines for the surgical treatment of esophageal achalasia.Surgical endoscopy · 2012Guideline
- Comparison between botulinum injection and removable covered self-expanding metal stents for the treatment of achalasia.Digestive diseases and sciences · 2013Trial
- Simultaneous surgical treatment of morbid obesity and end-stage achalasia: a case report and review of literature.Frontiers in surgery · 2026Article
- Spectrum of Esophageal Motility Disorders on High-Resolution Manometry in Patients With Non-obstructive Dysphagia.Cureus · 2025Article
- Challenges in Diagnosis and Treatment of Achalasia Cardia in Uganda: A Case Report of an Adolescent Female Presenting With Dysphagia.Case reports in surgery · 2025Article
- Infantile achalasia cardia: A rare case report of a 3-month-old female with recurrent pneumonia successfully treated with surgical intervention.International journal of surgery case reports · 2025Article
- Is Indocyanine Green the New Gold Standard for Checking Completion of Laparoscopic Heller's Cardiomyotomy?Cureus · 2024Article
- A Mechanics-Based Perspective on the Function of Human Sphincters During Functional Luminal Imaging Probe Manometry.Journal of biomechanical engineering · 2024Article
- Laparoscopic Heller Myotomy vs. Peroral Endoscopic Myotomy: an Analysis of the National Inpatient Sample Database.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023Article
- A mechanics-based perspective on the function of the esophagogastric junction during functional luminal imaging probe manometry.Biomechanics and modeling in mechanobiology · 2023Article
- Update on the Diagnosis and Treatment of Achalasia.Dysphagia · 2023Review
- MANAGEMENT OF SYMPTOMS RECURRENCE AFTER MYOTOMY FOR ACHALASIA. A PRACTICAL APPROACH.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2023Review
- Esophageal achalasia with severe malnutrition and liver enzyme elevation.Clinical journal of gastroenterology · 2022Article
- Article
- Intermittent neck swelling: an unusual presentation of achalasia cardia.BMJ case reports · 2021Article
- Thoracoscopic esophagectomy for esophageal carcinoma after peroral endoscopic myotomy for esophageal achalasia: a case report.Surgical case reports · 2021Article
- Intraoperative impedance planimetry (EndoFLIP™) results and development of esophagitis in patients undergoing peroral endoscopic myotomy (POEM).Surgical endoscopy · 2021Article
- A young lady with dysphagia.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2021Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Idiopathic achalasia is a rare primary motility disorder of the esophagus. The classical features are incomplete relaxation of a frequently hypertensive lower esophageal sphincter (LES) and a lack of peristalsis in the tubular esophagus. These motor abnormalities lead to dysphagia, stasis, regurgitation, weight loss, or secondary respiratory complications. Although major strides have been made in understanding the pathogenesis of this rare disorder, including a probable autoimmune mediated destruction of inhibitory neurons in response to an unknown insult in genetically susceptible individuals, a definite trigger has not been identified. The diagnosis of achalasia is suggested by clinical features and confirmed by further diagnostic tests, such as esophagogastroduodenoscopy (EGD), manometry or barium swallow. These studies are not only used to exclude pseudoachalasia, but also might help to categorize the disease by severity or clinical subtype. Recent advances in diagnostic methods, including high resolution manometry (HRM), might allow prediction of treatment responses. The primary treatments for achieving long-term symptom relief are surgery and endoscopic methods. Although limited high-quality data exist, it appears that laparoscopic Heller myotomy with partial fundoplication is superior to endoscopic methods in achieving long-term relief of symptoms in the majority of patients. However, the current clinical approach to achalasia will depend not only on patients' characteristics and clinical subtypes of the disease, but also on local expertise and patient preferences.
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