ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Stress/rest myocardial perfusion scintigraphy in patients without significant coronary artery disease.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Hybrid cardiac imaging: SPECT/CT and PET/CT. A joint position statement by the European Association of Nuclear Medicine (EANM), the European Society of Cardiac Radiology (ESCR) and the European Council of Nuclear Cardiology (ECNC).European journal of nuclear medicine and molecular imaging · 2011Guideline
- Prediction of outcome byJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Advanced imaging for risk stratification for ventricular arrhythmias and sudden cardiac death.Frontiers in cardiovascular medicine · 2022Review
- Can myocardial perfusion imaging predict outcome in patients with angina and ischemia but no obstructive coronary artery disease (INOCA)?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Prognostic value of myocardial perfusion imaging with D-SPECT camera in patients with ischemia and no obstructive coronary artery disease (INOCA).Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
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- Prognostic value of myocardial perfusion abnormalities for long-term prognosis in patients after coronary artery bypass grafting.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India · 2014Article
- Endothelial Dysfunction is Associated with Occult Coronary Artery Disease Detected by Positron Emission Tomography.IJC metabolic & endocrine · 2014Article
- Myocardial Perfusion SPECT Utility in Predicting Cardiovascular Events Among Indonesian Diabetic Patients.The open cardiovascular medicine journal · 2013Article
- The Role of Myocardial Perfusion Gated SPECT Study in Women with Coronary Artery Disease: A Correlative Study.Molecular imaging and radionuclide therapy · 2012Article
- The incremental value of coronary artery calcium scores to myocardial single photon emission computer tomography in risk assessment.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2011Review
- Imaging as an End Point in Ischemia Trials.Current cardiovascular imaging reports · 2011Article
- Comparative roles of cardiac CT and myocardial perfusion scintigraphy in the evaluation of patients with coronary artery disease: competitive or complementary.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2010Review
- Abnormal myocardial perfusion in the absence of anatomically significant coronary artery disease: implications and clinical significance.Journal of nuclear cardiology : official publication of the American Society of Nuclear CardiologyArticle
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo define the prognostic impact of stress myocardial perfusion scintigraphy (MPS) in patients with angiographic exclusion of significant coronary artery disease.
methodsAngiographic and MPS databases were matched to define patients without significant coronary artery disease by quantitative angiography (diameter stenosis <50%) who underwent stress MPS and coronary angiography within a time period of 3 months. A total of 118 patients were identified and followed for a mean of 6.3 +/- 1.2 years for death, a composite of death, myocardial infarction, bypass surgery, or percutaneous coronary intervention [MAE]) as well as occurrence of symptoms (angina or dyspnoe class CCS II to IV). Stress and rest MPS (using (99m)Tc-MIBI or tetrofosmin) were analyzed by quantitative perfusion SPECT (QPS) for summed stress and rest scores (SSS/SRS).
resultsThere were 16 deaths, 29 MAE, and 76 patients with MAE or significant symptoms during follow-up. Significant differences in SSS were found between patients who died (9.5 +/- 6.9 vs. 5.4 +/- 5.6, P = 0.012), had MAE (8.7 +/- 7.2 vs. 5.2 +/- 5.0, P = 0.010), or had MAE or significant clinical symptoms (7.2 +/- 7.1 vs. 4.6 +/- 6.2, P = 0.042) compared to those without the respective event. Logistic regression analysis demonstrated SSS to be a predictor of death (OR = 1.074 [95% CI: 1.004-1.149], P = 0.026) and MAE (OR = 1.087 [95% CI: 1.004-1.181], P = 0.027).
conclusionsIn patients without significant angiographic coronary artery disease, the result of stress MPS is a predictor of long-term prognosis. Quantitative analysis of MPS allows definition of patients with a higher likelihood to develop clinical events or symptoms.
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