ArticlePlant signaling & behavior2008
EL5 is involved in root development as an anti-cell death ubiquitin ligase.
Article in Plant signaling & behavior, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Using hyperspectral analysis as a potential high throughput phenotyping tool in GWAS for protein content of rice quality.Plant methods · 2019Article
- Rice ubiquitin ligase EL5 prevents root meristematic cell death under high nitrogen conditions and interacts with a cytosolic GAPDH.Plant signaling & behavior · 2015Article
- Profiling Gene Expression in GerminatingPlant molecular biology reporter · 2014Article
- The prolific ATL family of RING-H2 ubiquitin ligases.Plant signaling & behavior · 2012Review
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Ubiquitin ligase (E3) plays a central role in substrate recognition during ubiquitination, a post-translational modification of proteins. Rice EL5 is an E3 with a RING-H2 finger domain (RFD) and its transcript is upregulated by a chitin elicitor. The EL5-RFD has been intensively studied and demonstrated to exhibit E3 activity. Its three-dimensional structure was determined for the first time in plant E3, and the amino acid residues required for the interaction with the ubiquitin-conjugating enzyme (E2) were identified. Recent analyses revealed that EL5 plays a crucial role as an E3 in the maintenance of cell viability during root development in rice. In this addendum, we report that the EL5-RFD catalyzes polyubiquitination via the Lys48 residue of ubiquitin. We also discuss the possible role of EL5 as an anti-cell death enzyme. We hypothesize that EL5 might be responsible for mediating the degradation of cytotoxic proteins produced in root cells after the actions of phytohormones.
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