ArticlePlant signaling & behavior2007
Homologues of Arabidopsis Microtubule-Associated AIR9 in Trypanosomatid Parasites: Hints on Evolution and Function.
Article in Plant signaling & behavior, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Novel Cytoskeleton-Associated Proteins inMicroorganisms · 2021Article
- Division Plane Orientation Defects Revealed by a Synthetic Double Mutant Phenotype.Plant physiology · 2018Article
- The Trypanosoma brucei AIR9-like protein is cytoskeleton-associated and is required for nucleus positioning and accurate cleavage furrow placement.Molecular microbiology · 2012Article
- The integrity of the periplasmic domain of the VirA sensor kinase is critical for optimal coordination of the virulence signal response in Agrobacterium tumefaciens.Journal of bacteriology · 2011Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
AIR9 is an essential microtubule-associated protein from Arabidopsis. Sequence similarity searches indicate homologues of AIR9 in land plants and in excavate protists, including trypanosomatid parasites and Trichomonas. The AIR9-like protein from Trypanosoma brucei was recently detected in the proteome of the trypanosome flagellum, raising the possibility that trypanosomatid AIR9-like proteins also associate with microtubules. Because microtubule functions are essential to the viability of trypanosomatid parasites AIR9-like proteins may be exploited as drug targets without homology in humans. We further discuss the unexpected phylogeny of AIR9-like proteins from plants and protozoans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.