ArticlePlant signaling & behavior2006
The Twisted Dwarf's ABC: How Immunophilins Regulate Auxin Transport.
Article in Plant signaling & behavior, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 21 citations in OpenAlex.
- Article
- A Retro-Perspective on Auxin Transport.Frontiers in plant science · 2021Article
- Auxin-transporting ABC transporters are defined by a conserved D/E-P motif regulated by a prolylisomerase.The Journal of biological chemistry · 2020Article
- Plant hormone transporters: what we know and what we would like to know.BMC biology · 2017Review
- Mechanisms of thaxtomin A-induced root toxicity revealed by a thaxtomin A sensitive Arabidopsis mutant (ucu2-2/gi-2).Plant cell reports · 2016Article
- Polar auxin transport is essential for medial versus lateral tissue specification and vascular-mediated valve outgrowth in Arabidopsis gynoecia.Plant physiology · 2014Article
- Regulation of ABCB1/PGP1-catalysed auxin transport by linker phosphorylation.The EMBO journal · 2012Article
- Tail-anchored membrane proteins: exploring the complex diversity of tail-anchored-protein targeting in plant cells.Plant cell reports · 2011Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is increasing evidence that immunophilins function as key regulators of plant development. One of the best investigated members, the multi-domain FKBP TWISTED DWARF1 (TWD1)/FKBP42, has been shown to reside on both the vacuolar and plasma membranes where it interacts in mirror image with two pairs of ABC transporters, MRP1/ MRP2 and PGP1/PGP19(MDR1), respectively. Twisted dwarf1 and pgp1/pgp19 mutants display strongly overlapping phenotypes, including reduction and disorientation of growth, suggesting functional interaction.In a recent work using plant and heterologous expression systems, TWD1 has been demonstrated to modulate PGP-mediated export of the plant hormone auxin, which controls virtually all plant developmental processes. Here we summarize recent molecular models on TWD1 function in plant development and PGP-mediated auxin tranport and discuss open questions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.