ArticlePlant signaling & behavior2007
Interplay among nitric oxide and reactive oxygen species: a complex network determining cell survival or death.
Article in Plant signaling & behavior, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Neuroprotective Effects of Resveratrol in In vivo and In vitro Experimental Models of Parkinson's Disease: a Systematic Review.Neurotoxicity research · 2022Pooled it
- Enhancement of the Antioxidant and Anti-Inflammatory Effects of Jeju Beetroot (Preventive nutrition and food science · 2026Article
- Redox signaling in the heart and brain: the roles of nitric oxide and reactive oxygen species in disease and therapy.Metabolic brain disease · 2026Review
- The role of periodontitis in cancer development, with a focus on oral cancers.Molecular biology reports · 2024Review
- Induction of Nitric Oxide and Its Role in Facial Nerve Regeneration According to the Method of Facial Nerve Injury.Antioxidants (Basel, Switzerland) · 2024Review
- Unraveling Metal-Ligand Bonding in an HNO-Evolving {FeNO}Journal of the American Chemical Society · 2023Article
- Article
- Antioxidant and Anti-Inflammatory Activity ofMolecules (Basel, Switzerland) · 2022Article
- Arsenic alters nitric oxide signaling similar to autism spectrum disorder and Alzheimer's disease-associated mutations.Translational psychiatry · 2022Article
- Rhizosphere inoculation ofFrontiers in plant science · 2022Article
- Redox post-translational modifications and their interplay in plant abiotic stress tolerance.Frontiers in plant science · 2022Review
- Opposite Modulatory Effects of Crataegus aronia Aqueous Extract on Platelet Aggregation in Rats.Chinese journal of integrative medicine · 2021Article
- Exposure to low doses of pesticides induces an immune response and the production of nitric oxide in honeybees.Scientific reports · 2021Article
- Genome-Wide Identification of Wheat ZIP Gene Family and Functional Characterization of theFrontiers in plant science · 2021Article
- Antioxidant and Neuroprotective Effects of Caffeine against Alzheimer's and Parkinson's Disease: Insight into the Role of Nrf-2 and A2AR Signaling.Antioxidants (Basel, Switzerland) · 2020Review
- Allies or Enemies: The Role of Reactive Oxygen Species in Developmental Processes of Black Cottonwood (Antioxidants (Basel, Switzerland) · 2020Article
- Article
- Nitric Oxide Enhances Cytotoxicity of Lead by Modulating the Generation of Reactive Oxygen Species and Is Involved in the Regulation of PbPlants (Basel, Switzerland) · 2019Article
- Sargassum sagamianum extract protects INS-1 pancreatic β cells against high glucose-induced apoptosis.Cytotechnology · 2019Article
- Xylopine Induces Oxidative Stress and Causes GOxidative medicine and cellular longevity · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Programmed cell death (PCD) is an integrated cellular process occurring in plant growth, development, and defense responses to facilitate normal growth and development and better survival against various stresses as a whole. As universal toxic chemicals in plant and animal cells, reactive oxygen or nitrogen species (ROS or RNS), mainly superoxide anion (O(2) (-*)), hydrogen peroxide (H(2)O(2)) or nitric oxide ((*)NO), have been studied extensively for their roles in PCD induction. Physiological and genetic studies have convincingly shown their essential roles. However, the details and mechanisms by which ROS and (*)NO interplay and induce PCD are not well understood. Our recent study on Cupressus lusitanica culture cell death revealed the elicitor-induced co-accumulation of ROS and (*)NO and interactions between (*)NO and H(2)O(2) or O(2)-(*) in different ways to regulate cell death. (*)NO and H(2)O(2) reciprocally enhanced the production of each other whereas (*)NO and O(2) (-*) showed reciprocal suppression on each other's production. It was the interaction between (*)NO and O(2)-(*) but not between (*)NO and H(2)O(2) that induced PCD, probably through peroxynitrite (ONOO(-)). In this addendum, some unsolved issues in the study were discussed based on recent studies on the complex network of ROS and (*)NO leading to PCD in animals and plants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.