Evidence map›Paper›PMID 19703589›Full record

ArticleGene expression patterns : GEP2009

Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.

Ilaria Stanghellini, Geppino Falco, Sung-Lim Lee, Manuela Monti, Minoru S H Ko

Abstract read
In one paragraph

Article in Gene expression patterns : GEP, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ilaria StanghelliniDevelopmental Genomics and Aging Section, Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
Geppino Falco
Sung-Lim Lee
Manuela Monti
Minoru S H Ko
National Institutes of Health · US

Funding

Cellular commitment to mortality: analyses of mouse early embryoZIAAG000655 · NIA · NATIONAL INSTITUTE ON AGING · PI SCHLESSINGER, DAVID · 2009 to 2013
$2.8M
Function of Zscan4 in ES cells and early embryosZIAAG000706 · NIA · NATIONAL INSTITUTE ON AGING · PI KO, MINORU · 2009 to 2011
$1.4M
Cellular Commitment To Mortality:Mouse Early EmbryoZ01AG000655 · NIA · NATIONAL INSTITUTE ON AGING · PI KO, MINORU S · 1999 to 2008
$944k
TRANSCRIPTIONAL CONTROL ELEMENTS IN THE GIBBON APE LEUKEMIA VIRUS LTRZ01AG000706 · NIA · NATIONAL INSTITUTE ON AGING · PI KO, MINORU · 1986 to 2008
$337k
Reprogramming in mouse early embryosZ01AG000677 · NIA · NATIONAL INSTITUTE ON AGING · PI KO, MINORU · 2008 to 2008
$303k
Reprogramming in mouse early embryosZIAAG000677 · NIA · NATIONAL INSTITUTE ON AGING · PI KO, MINORU · 2009 to 2009
$203k
Intramural NIH HHS Z01 AG000655Intramural NIH HHS Z01 AG000677Intramural NIH HHS Z01 AG000706
6 · The paper itself

Abstract

We describe the identification and characterization of Trim43a, Trim43b, and Trim43c genes, whose expression are restricted to preimplantation stages and peak at the 8-cell to morula stage. We identified a 5kb DNA fragment that covers upstream region of Trim43a as a putative promoter, which can drive the expression of mStrawberry fluorescent protein in a manner similar to endogenous Trim43 genes. Trim43 genes will be useful stage-specific markers for the study of preimplantation embryos.

Indexed as

Gene Expression Regulation, DevelopmentalAnimalsBase SequenceBlastocystEmbryonic DevelopmentMiceMolecular Sequence DataMorula

Identifiers

PMID19703589
PMCPMC2784184
OpenAlexW2075088565

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.